Recent Updates
Recently added Catalysts

Keppra

Phase 1

Healthy | Small molecule | Other |Teva Pharmaceutical Industries Limited|Last Updated: Aug 20, 2024

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials4
Total Enrollment96

FDA Designations

No designations recorded

Clinical trial landscape

Keppra · 4 trials · 1 indication

Phase 1 4
NCT00859430Levetiracetam 1000 mg Under Non-Fasting ConditionsHealthy
COMPLETED22 Analytics
NCT00859521Levetiracetam 1000 mg Under Fasting ConditionsHealthy
COMPLETED30 Analytics
NCT00849485Levetiracetam 750 mg Tablets Under Non-Fasting ConditionsHealthy
COMPLETED22 Analytics
NCT00849862Levetiracetam 750 mg Tablets Under Fasting ConditionsHealthy
COMPLETED22 Analytics
PHASE1COMPLETED
Levetiracetam 1000 mg Under Non-Fasting Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Levetiracetam 1000 mg Under Fasting Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Levetiracetam 750 mg Tablets Under Non-Fasting Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Levetiracetam 750 mg Tablets Under Fasting Conditions
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Cmax - Maximum Observed Concentration
Blood samples collected over 36 hour period

Bioequivalence based on Cmax

AUC0-inf - Area Under the Concentration-time Curve From Time Zero to Infinity (Extrapolated)
Blood samples collected over 36 hour period

Bioequivalence based on AUC0-inf

AUC0-t - Area Under the Concentration-time Curve From Time Zero to Time of Last Non-zero Concentration (Per Participant)
Blood samples collected over 36 hour period

Bioequivalence based on AUC0-t

AUC0-t - Area Under Concentration-time Curve From Time Zero to Time of Last Non-zero Concentration (Per Participant)
Blood samples collected over 36 hour period

Bioequivalence based on AUC0-t

Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
LevetiracetamEXPERIMENTALLevetiracetam 1000 mg Tablet (test) dosed in first period followed by Keppra® 1000 mg Tablet (reference) dosed in second period
Keppra®ACTIVE_COMPARATORKeppra® 1000 mg Tablet (reference) dosed in first period followed by Levetiracetam 1000 mg Tablet (test) dosed in second period

Interventions

NameTypeDescription
LevetiracetamDRUG1000 mg Tablet
Keppra®DRUG1000 mg Tablet
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria All subjects must satisfy the following criteria to be considered for study participation: * Subject must be male or non-pregnant, non-breast-feeding female * Subject must be at least 18 years of age * Subject must have a Body Mass Index (BMI) between 19 and 30 kg/m2, inclusive,...

Countries:United StatesCanada
Unlock Eligibility Criteria

Frequently asked questions about Keppra

What is Keppra used for?

Keppra is the brand name for levetiracetam, a small molecule drug being studied in healthy volunteers. The clinical trials listed for Keppra are bioavailability studies conducted under fasting and non-fasting conditions, which are typical for assessing how the drug is absorbed and processed in the body.

Who makes Keppra?

Keppra is developed by Teva Pharmaceutical Industries Limited, a company traded on the stock exchange under the ticker TEVA. The drug is being studied in Phase 1 clinical trials.

What phase is Keppra in?

Keppra is in Phase 1 clinical development. All four clinical trials listed for Keppra are Phase 1 studies, and they have all been completed. Keppra is an investigational drug in this context, and it is not approved for any medical use based on the available information.

What clinical trials is Keppra in?

Keppra has been studied in four completed Phase 1 clinical trials. These include NCT00849485 and NCT00849862, which tested 750 mg tablets under non-fasting and fasting conditions in Canada, and NCT00859430 and NCT00859521, which tested 1000 mg tablets under non-fasting and fasting conditions in the United States.

Is Keppra the same as levetiracetam?

Yes, Keppra is the brand name for levetiracetam. The clinical trials for Keppra are titled with levetiracetam, such as "Levetiracetam 750 mg Tablets Under Non-Fasting Conditions" and "Levetiracetam 1000 mg Under Fasting Conditions."