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Finasteride

Phase 1

Healthy | Small molecule | Other |Teva Pharmaceutical Industries Limited|Last Updated: Aug 19, 2024

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials2
Total Enrollment52

FDA Designations

No designations recorded

Clinical trial landscape

Finasteride · 2 trials · 1 indication

Phase 1 2
NCT00835666Finasteride 5 mg Tablets Under Fasting ConditionsHealthy
COMPLETED32 Analytics
NCT00835796Finasteride 5 mg Tablets, Non-fastingHealthy
COMPLETED20 Analytics
PHASE1COMPLETED
Finasteride 5 mg Tablets Under Fasting Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Finasteride 5 mg Tablets, Non-fasting
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Cmax - Maximum Observed Concentration
Blood samples collected over 36 hour period

Bioequivalence based on Cmax

AUCinf - Area Under the Concentration-time Curve From Time Zero to Infinity (Extrapolated)
Blood samples collected over 36 hour period

Bioequivalence based on AUCinf

AUC0-t - Area Under the Concentration-time Curve From Time Zero to Time of Last Non-zero Concentration (Per Participant)
Blood samples collected over 36 hour period

Bioequivalence based on AUC0-t

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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
FinasterideEXPERIMENTALFinasteride 5 mg Tablet (test) dosed in first period followed by Proscar® 5 mg Tablet (reference) dosed in second period
Proscar®ACTIVE_COMPARATORProscar® 5 mg Tablet (reference) dosed in first period followed by Finasteride 5 mg Tablet (test) dosed in second period

Interventions

NameTypeDescription
Finasteride 5 mg tabletsDRUG1 x 5 mg, single dose fasting
PROSCAR®DRUG1 x 5 mg, single dose fasting
PROSCAR® 5mg tabletsDRUG1 x 5 mg, single dose fasting
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Eligibility Criteria

Age Range18 Years to N/A
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * All subjects selected for this study will be male non-smokers at least 18 years of age. Subjects will have a BMI (body mass index) of 30 or less. * Each subject shall be given a general physical examination within 28 days of initiation of the study. Such examination includes, ...

Countries:United States
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Frequently asked questions about Finasteride

What is Finasteride used for?

Finasteride is a small molecule drug being developed by Teva Pharmaceutical Industries Limited. In the clinical trials listed, it is being studied in healthy male volunteers to assess the pharmacokinetics of 5 mg tablets under fasting and non-fasting conditions. The drug is currently in Phase 1 clinical development.

Who makes Finasteride?

Finasteride is being developed by Teva Pharmaceutical Industries Limited, which is publicly traded under the ticker TEVA. The company is conducting Phase 1 clinical trials to evaluate the drug's pharmacokinetics in healthy volunteers.

What phase is Finasteride in?

Finasteride is in Phase 1 clinical development. Two Phase 1 trials have been completed, both involving healthy male volunteers. The drug is investigational and has not been approved for any indication based on the data provided.

What clinical trials is Finasteride in?

Finasteride has two completed Phase 1 trials: NCT00835666, a fasting study with 32 participants, and NCT00835796, a non-fasting study with 20 participants. Both trials enrolled healthy males aged 18 years and older in the United States.

Is Finasteride the same as Propecia or Proscar?

The data provided does not list alternative names for Finasteride. The drug is being studied as 5 mg tablets in clinical trials. No other names are mentioned in the available information.