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DR-104

Phase 3

Emergency Contraception | Small molecule | Other |Teva Pharmaceutical Industries Limited|Last Updated: Oct 18, 2012

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment343

FDA Designations

No designations recorded

Clinical trial landscape

DR-104 · 1 trial · 1 indication

Phase 3 1
NCT00777556Emergency Contraception Actual Use StudyEmergency Contraception
COMPLETED343 Analytics
PHASE3COMPLETED
Emergency Contraception Actual Use Study
Emergency ContraceptionUnlock trial analytics

Study Endpoints

Primary Endpoints

Percentage of Participants Who Appropriately Self-selected DR-104 (Plan B® 1.5) When Dispensed Under Simulated Over-the-counter (OTC) Conditions
Day 1

The percentage of participants who appropriately self-selected Plan B® 1.5 at the Screening/Enrollment Visit after reading the product label. Following the standard norms for a therapy to over-the-counter (Rx-to-OTC) switch process, this outcome is an evaluation of potential consumers' ability to self-diagnose the condition and that treatment with the product is appropriate for them.

Percentage of Participants Who Correctly Used DR-104 When Dispensed Under Simulated OTC Conditions
Week 1

The percentage of participants who having appropriately self-selected and been dispensed Plan B® 1.5, correctly used it according to product labeling. Correct use was considered to have occurred if participants reported at the Week 1 follow-up contact that she took Plan B® 1.5 within 72 hours following unprotected sexual intercourse. Following the standard norms for a therapy to over-the-counter (Rx-to-OTC) switch process, this outcome is an evaluation of potential consumers' ability to self-treat with the product according to the product instructions.

Secondary Endpoints

Participants With Treatment-Emergent Adverse Events (TEAE)
Day 1 to week 8
Participants Summarized by Repeat Use of Emergency Contraception (EC)
up to week 8
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
DR-104EXPERIMENTALOne tablet for emergency contraception

Interventions

NameTypeDescription
DR-104DRUGOne 1.5 mg tablet of levonorgestrel for emergency contraception within 72 hours following unprotected sexual intercourse.
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Eligibility Criteria

Age Range11 Years to 16 Years
SexFEMALE
Healthy VolunteersYes
Study Sites5

Inclusion Criteria: * Female and 11-16 years of age, inclusive * Subject must be requesting emergency contraception for her own use (not for use by another person) and for current (not future) use * Subject can read and understand English, according to her own judgment * Others as dictated by FDA-a...

Countries:United States
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Frequently asked questions about DR-104

What is DR-104 used for?

DR-104 is an investigational small molecule being developed for emergency contraception. It is intended for use as an emergency contraceptive to prevent pregnancy after unprotected intercourse or contraceptive failure.

Who makes DR-104?

DR-104 is being developed by Teva Pharmaceutical Industries Limited, which trades under the ticker TEVA. The company is conducting clinical development of this investigational emergency contraceptive.

What phase is DR-104 in?

DR-104 is in Phase 3 clinical development. It has completed one Phase 3 trial, and it remains an investigational drug that has not been approved by regulatory authorities.

What clinical trials is DR-104 in?

DR-104 has one completed Phase 3 clinical trial, NCT00777556, titled "Emergency Contraception Actual Use Study." This study enrolled 343 female participants aged 11 years and older in the United States and evaluated the drug in a real-world setting.

Is DR-104 the same as any other drug?

No alternative names for DR-104 have been disclosed. It is identified solely by its developmental code DR-104 in clinical trial records and by the developer.