Recent Updates
Recently added Catalysts

Cilostazol

Phase 1

Healthy | Small molecule | Other |Teva Pharmaceutical Industries Limited|Last Updated: Aug 20, 2024

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials2
Total Enrollment66

FDA Designations

No designations recorded

Clinical trial landscape

Cilostazol · 2 trials · 1 indication

Phase 1 2
NCT00839930Cilostazol 50 mg Tablets Under Fasting ConditionsHealthy
COMPLETED30 Analytics
NCT00838630Cilostazol 100 mg Tablet Formulations Under Fasting ConditionsHealthy
COMPLETED36 Analytics
PHASE1COMPLETED
Cilostazol 50 mg Tablets Under Fasting Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Cilostazol 100 mg Tablet Formulations Under Fasting Conditions
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Cmax - Maximum Observed Concentration
Blood samples collected over 72 hour period

Bioequivalence based on Cmax

AUC0-inf - Area Under the Concentration-time Curve From Time Zero to Infinity (Extrapolated)
Blood samples collected over 72 hour period

Bioequivalence based on AUC0-inf

AUC0-t - Area Under the Concentration-time Curve From Time Zero to Time of Last Non-zero Concentration
Blood samples collected over 72 hour period

Bioequivalence based on AUC0-t

Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
Cilostazol (test)EXPERIMENTALCilostazol 50 mg Tablet (test) dosed in first period followed by Pletal® 50 mg Tablet (reference) dosed in second period
Pletal® (reference)ACTIVE_COMPARATORPletal® 50 mg Tablet (reference) dosed in first period followed by Cilostazol 50 mg Tablet (test) dosed in second period.
1EXPERIMENTAL -
2ACTIVE_COMPARATOR -

Interventions

NameTypeDescription
Cilostazol 50 mg TabletsDRUG1 x 50 mg, single-dose fasting
Pletal®DRUG1 x 50 mg, single-dose tablet
Cilostazol 100 mg tabletsDRUG1 x 100 mg
Pletal® 100 mg tabletsDRUG1 x 100 mg
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Screening Demographics: All volunteers selected for this study will be healthy men or women 18 years of age or older at the time of dosing. The volunteer's body mass index (BMI) is less than or equal to 30. * Screening Procedures: Each volunteer will complete the screening pro...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about Cilostazol

What is Cilostazol used for?

Cilostazol is a small molecule drug being studied in healthy volunteers. It is currently in Phase 1 clinical development, with two completed trials evaluating different tablet formulations under fasting conditions. The drug is being developed by Teva Pharmaceutical Industries Limited.

Who makes Cilostazol?

Cilostazol is being developed by Teva Pharmaceutical Industries Limited, a company traded on the stock exchange under the ticker TEVA. The drug is currently in Phase 1 clinical development, with two completed trials in healthy volunteers.

What phase is Cilostazol in?

Cilostazol is in Phase 1 clinical development. Two Phase 1 trials have been completed, both involving healthy volunteers. The trials studied 100 mg and 50 mg tablet formulations under fasting conditions. The drug is not yet approved and remains investigational.

What clinical trials is Cilostazol in?

Cilostazol has two completed Phase 1 clinical trials. NCT00838630 studied 100 mg tablet formulations under fasting conditions with 36 participants. NCT00839930 studied 50 mg tablets under fasting conditions with 30 participants. Both trials were conducted in the United States with healthy volunteers aged 18 years and older.

Is Cilostazol FDA approved?

Cilostazol is not FDA approved. It is an investigational drug currently in Phase 1 clinical development. Two Phase 1 trials have been completed in healthy volunteers, but the drug has not yet received regulatory approval.