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CEP-10953

Phase 3

Narcolepsy | Small molecule | Neurology |Teva Pharmaceutical Industries Limited|Last Updated: Jul 19, 2013

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment328

FDA Designations

No designations recorded

Clinical trial landscape

CEP-10953 · 1 trial · 4 indications

Phase 3 1
NCT00078312Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep DisorderNarcolepsy
COMPLETED328 Analytics
PHASE3COMPLETED
Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder
NarcolepsyUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and Tolerability as Measured by Number of Participants With Adverse Events
Screening/Baseline and months 1, 3, 6, 9, and 12 and every 3 months thereafter

Serious and Non-serious Adverse Events (SAEs). Serious adverse event is any adverse event occurring at any dose that results in any of the following outcomes: death, life-threatening, inpatient hospitalization, persistent or significant disability, congenital anomaly, or an important medical event. An adverse event that does not meet any of the criteria for seriousness listed previously will be regarded as a nonserious adverse event.

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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
CEP-10953 (Armodafinil)DRUGArmodafinil (po) 100 to 250 mg/day up to 12 months
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites50

Inclusion Criteria: Patients are included in the study if all of the following criteria are met: 1. Written informed consent is obtained. 2. Men and women (outpatients) of any ethnic origin, between 18 and 65 years of age (inclusive) are eligible. 3. The patient has a complaint of excessive sleepi...

Countries:United StatesRussia
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Frequently asked questions about CEP-10953

What is CEP-10953 used for?

CEP-10953 is an investigational small molecule being studied for the treatment of narcolepsy. It is in Phase 3 clinical development for this indication. The drug is being developed by Teva Pharmaceutical Industries Limited (TEVA).

What does CEP-10953 target?

CEP-10953 is a small molecule being studied for narcolepsy. Its specific molecular target has not been disclosed in the available information. The drug is in Phase 3 clinical development for this indication.

Who makes CEP-10953?

CEP-10953 is being developed by Teva Pharmaceutical Industries Limited, which trades under the ticker TEVA. The drug is a small molecule in Phase 3 clinical development for the treatment of narcolepsy.

What phase is CEP-10953 in?

CEP-10953 is in Phase 3 clinical development for narcolepsy. It is an investigational drug and has not been approved by regulatory authorities. One Phase 3 trial has been completed for this indication.

What clinical trials is CEP-10953 in?

CEP-10953 has one completed Phase 3 trial, NCT00078312, which enrolled 328 participants. The trial studied the drug for narcolepsy, obstructive sleep apnea/hypopnea syndrome, and chronic shift work sleep disorder in the United States and Russia.

Is CEP-10953 the same as armodafinil?

CEP-10953 is also known as armodafinil. The completed Phase 3 trial NCT00078312 was titled 'Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder.'