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Armodafinil 100 to/day

Phase 3

Excessive Daytime Sleepiness | Small molecule | Neurology |Teva Pharmaceutical Industries Limited|Last Updated: Jul 19, 2013

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment743

FDA Designations

No designations recorded

Clinical trial landscape

Armodafinil 100 to/day · 1 trial · 4 indications

Phase 3 1
NCT00228553Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive SleepinessExcessive Daytime Sleepiness
COMPLETED743 Analytics
PHASE3COMPLETED
Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness
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Study Endpoints

Primary Endpoints

Safety and Tolerability in This Patient Population (Narcolepsy, OSAHS, SWSD) Over Time (up to 2 Years)
End of months 1, 3, 6, 9, and 12 and every 3 months for up to an additional year

An adverse event is any untoward medical occurrence in a patient that develops or worsens in severity during the conduct of a clinical study. Serious and Non-serious Adverse Events (SAEs). Serious adverse event is any adverse event occurring at any dose that results in any of the following outcomes: death, life-threatening, inpatient hospitalization, persistent or significant disability, congenital anomaly, or an important medical event. An adverse event that does not meet any of the criteria for seriousness listed previously will be regarded as a nonserious adverse event.

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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelFACTORIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTALArmodafinil 100 to 250 mg/day

Interventions

NameTypeDescription
Armodafinil 100 to 250 mg/dayDRUGArmodafinil 100-250 mg: once daily in the morning for patients with obstructive sleep apnea/hypopnea syndrome (OSAHS) or narcolepsy, once daily only on nights worked for patients with shift worker sleep disorder (SWSD).
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites100

Inclusion Criteria: Patients are included in the study if all of the following criteria are met: * Men and women (outpatients) of any ethnic origin, between 18 and 65 years of age (inclusive) at the beginning of the respective double-blind study, are eligible. * The patient has completed a cephalo...

Countries:United StatesAustraliaCanadaFranceGermanyPuerto RicoRussia
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Frequently asked questions about Armodafinil 100 to/day

What is Armodafinil 100 to/day used for?

Armodafinil 100 to/day is used for the treatment of excessive daytime sleepiness. It is being developed as a small molecule therapy in the neurology therapeutic area. The drug is currently in Phase 3 clinical development and is intended to address conditions characterized by excessive sleepiness.

Who makes Armodafinil 100 to/day?

Armodafinil 100 to/day is being developed by Teva Pharmaceutical Industries Limited, a company traded under the ticker symbol TEVA. The drug is currently in Phase 3 clinical development for the treatment of excessive daytime sleepiness.

What phase is Armodafinil 100 to/day in?

Armodafinil 100 to/day is in Phase 3 clinical development. It is an investigational drug being studied for the treatment of excessive daytime sleepiness. The drug has completed one Phase 3 trial and is not yet approved by regulatory authorities.

What clinical trials is Armodafinil 100 to/day in?

Armodafinil 100 to/day has been studied in one completed Phase 3 clinical trial, identified as NCT00228553. This trial was an extension study evaluating the safety and efficacy of armodafinil in patients with excessive sleepiness, including those with narcolepsy, obstructive sleep apnea/hypopnea syndrome, and chronic shift work sleep disorder.

Is Armodafinil 100 to/day the same as Armodafinil?

Armodafinil 100 to/day is a specific dosage form of armodafinil, which is the active pharmaceutical ingredient. The drug is being developed by Teva Pharmaceutical Industries Limited for the treatment of excessive daytime sleepiness. The clinical trial NCT00228553 evaluated the safety and efficacy of armodafinil in this patient population.