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TRS01 eye

Phase 1

Non-infectious Anterior Uveitis | Small molecule | Ophthalmology |Tarsier Pharma Ltd.|Last Updated: Oct 5, 2023

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment16

FDA Designations

No designations recorded

Clinical trial landscape

TRS01 eye · 2 trials · 2 indications

Phase 1 2
NCT04222712A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior UveitisNon-infectious Anterior Uveitis
COMPLETED16 Analytics
NCT04222725A Study of TRS01 in Participants With Post-surgical Ocular InflammationPost Surgical Ocular Inflammation
COMPLETED37 Analytics
PHASE1COMPLETED
A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis
Non-infectious Anterior UveitisUnlock trial analytics
PHASE1COMPLETED
A Study of TRS01 in Participants With Post-surgical Ocular Inflammation
Post Surgical Ocular InflammationUnlock trial analytics

Study Endpoints

Primary Endpoints

Assessment of Both Systemic and Ocular Adverse Events
10 weeks

Number of patients experiencing Adverse Events during the study

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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
TRS01 low doseEXPERIMENTAL -
TRS01 high doseEXPERIMENTAL -
TRS01 medium doseEXPERIMENTAL -
PlaceboPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
TRS01 eye dropsDRUGDosed four times a day (QID)
Placebo eye dropsDRUGDosed QID
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * 18 years of age or older * Able to provide informed consent, follow instructions and complete all required study visits for the duration of the study. * Diagnosed with active non-infectious anterior uveitis requiring an increase or initiation of topical steroids for management...

Countries:United States
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Frequently asked questions about TRS01 eye

What is TRS01 eye used for?

TRS01 eye is an investigational small molecule eye drop being developed for non-infectious anterior uveitis and post-surgical ocular inflammation. It is currently in Phase 1 clinical development and has not been approved by the FDA.

What does TRS01 eye target?

TRS01 eye is a small molecule, but its specific molecular target has not been disclosed. It is being studied for its effects on ocular inflammation in conditions like non-infectious anterior uveitis and post-surgical ocular inflammation.

Who makes TRS01 eye?

TRS01 eye is being developed by Tarsier Pharma Ltd., a biopharmaceutical company. The company's ticker symbol is TARX.

What phase is TRS01 eye in?

TRS01 eye is in Phase 1 clinical development. It is an investigational drug and has not been approved by the FDA. Two Phase 1 trials have been completed.

What clinical trials is TRS01 eye in?

TRS01 eye has been studied in two completed Phase 1 trials: NCT04222712 for active non-infectious anterior uveitis and NCT04222725 for post-surgical ocular inflammation. Both trials were conducted in the United States.

Is TRS01 eye the same as TRS01?

TRS01 eye is the eye drop formulation of TRS01, a small molecule being developed by Tarsier Pharma Ltd. The drug is referred to as TRS01 eye in clinical trials for ocular conditions.