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Last traded Jun 30, 2025. This price is not current.
FDA decisions, readouts and PDUFA dates · scored by probability of approval
| Catalyst | Drug / Treatment | Stage | Prob. of Approval | Description | Drug Type | Therapeutic Area | Source |
|---|
Dated clinical, regulatory and corporate events for SpringWorks Therapeutics, Inc.
How SWTX actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2025-12-31 | SW-3431 | IND Submission | IND |
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SW-682 Small moleculeNCT06251310 | Advanced Solid Tumor | Phase 1 | RECRUITING | 186 | Jan 18, 2027 | ||||||
| Nirogacestat Small moleculeMarketedNCT07170644 | Desmoid Tumor | Approved | ACTIVE NOT_RECRUITING | 190 | Oct 9, 2029 | ||||||
| Mirdametinib Small moleculeMarketedNCT03962543 | Plexiform Neurofibroma | Approved | ACTIVE NOT_RECRUITING | 114 | Dec 22, 2028 | ||||||
| Nirogacestat Small moleculeMarketedNCT05879146 | Tumor | Approved | RECRUITING | 40 | Jan 31, 2028 | ||||||
| Mirdametinib Small moleculeMarketedNCT06159166 | NF1 | Approved | RECRUITING | 24 | Nov 15, 2028 | ||||||
| Nirogacestat Small moleculeNot countedNCT05348356 | Ovarian Granulosa-Stromal Tumor | Phase 2 | COMPLETED | 53 | Jul 14, 2025 |
Readouts, endpoints and source filings for every SWTX program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| OGSIVEO | desmoid tumors | Phase 3 | 2025-10-21 | 34.3% (n = 24) in year 1; 45.7% (n = 32) in patients who received OGSIVEO for up to 4 years; 24 (34.3%) PRs and 8 (11.4%) CRs in total; −32.3% at year one (n=46); −75.8% (n=15) for patients completing at least four years of treatmentRead More | SpringWorks Therapeutics Announces Publication of Long-Term Efficacy and Safety Data from the Phase 3 DeFi Trial of OGSIVEO (nirogacestat) in Adults with Desmoid Tumors in the Journal of Clinical OncologyRead More |
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| Edris BadreddinOfficer (Chief Operating Officer) | Sell | -3,924 185,788 held | $53.12 | 03/03/2025 |
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 0.2 % | 3.49 M | 74.27 K |
Shares sold short, counted twice a month.
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
|---|
| Calls | Strike | Puts | ||||
|---|---|---|---|---|---|---|
| Last | Vol | OI | Last | Vol | OI | |
| No data available | ||||||
How SWTX ranks across every disease it competes in