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Verorab

Phase 3

Rabies | Monoclonal antibody | Infectious Disease |Sinovac Biotech, Ltd|Last Updated: Jul 9, 2025

Target and mechanism

ModalityMonoclonal antibody

Also known as Verorab®

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindACTIVE_CONTROLLEDDMC
Total Trials2
Total Enrollment510

FDA Designations

No designations recorded

Clinical trial landscape

Verorab · 2 trials · 1 indication

Phase 3 1Phase 2 1
NCT07055295Immunogenicity and Safety of Rabies Vaccine (Serum-free Vero Cell) in a Pre-exposure Prophylaxis RegimenRabies
NOT YET_RECRUITING390 Analytics
PHASE3NOT YET_RECRUITING
Immunogenicity and Safety of Rabies Vaccine (Serum-free Vero Cell) in a Pre-exposure Prophylaxis Regimen
RabiesUnlock trial analytics

Study Endpoints

Primary Endpoints

Proportion of participants achieving a RVNA titer ≥0.5 IU/mL
Day 42 after the first dose of vaccination

Secondary Endpoints

GMCs of RVNA titers
Day 28 and Day 42 after the first dose of vaccination
Incidence of adverse reactions
Up to 28 days after the last-dose vaccination
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
Sinovac rabies vaccineEXPERIMENTALParticipants will be randomly assigned to receive Sinovac rabies vaccine.
Sanofi Pasteur Verorab®ACTIVE_COMPARATORParticipants will be randomly assigned to receive the marketed rabies vaccine Verorab®

Interventions

NameTypeDescription
Rabies Vaccine (Serum-free Vero Cell), Freeze-driedBIOLOGICALReceiving three doses of rabies vaccine rabies vaccine manufactured by Sinovac using a three-dose PrEP schedule
Verorab®BIOLOGICALReceiving three doses of marketed rabies vaccine manufactured by Sanofi using the three-dose PrEP schedule
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Eligibility Criteria

Age Range1 Year to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Populations aged ≥1 years old; 2. Participants and/or participants' parents/legal guardians are able to understand and sign the informed consent form (ICF) voluntarily; 3. Participants are able to comply with the study procedures based on the investigator's assessment; 4. In ...

Countries:Pakistan
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Frequently asked questions about Verorab

What is Verorab used for?

Verorab is a rabies vaccine used for pre-exposure prophylaxis against rabies. It is being investigated in clinical trials for the prevention of rabies in healthy individuals. The vaccine is currently in clinical development and is not yet approved for use.

Who makes Verorab?

Verorab is being developed by Sinovac Biotech, Ltd, a biopharmaceutical company. The company's stock is traded under the ticker symbol SVA. Sinovac is conducting clinical trials to evaluate the vaccine's safety and immunogenicity.

What phase is Verorab in?

Verorab is in Phase 3 clinical development. It is being studied in a Phase 3 trial for pre-exposure prophylaxis against rabies. The vaccine is investigational and has not yet received regulatory approval. Additional Phase 2 trials are also ongoing.

What clinical trials is Verorab in?

Verorab is being evaluated in two clinical trials. NCT07055295 is a Phase 3 study of immunogenicity and safety in a pre-exposure prophylaxis regimen with 390 participants. NCT07055880 is a Phase 2 dose-finding study with 120 participants. Both trials are not yet recruiting and are being conducted in Pakistan.

Is Verorab the same as Verorab®?

Yes, Verorab and Verorab® refer to the same rabies vaccine. The registered trademark symbol is used in the product name. The vaccine is being developed by Sinovac Biotech, Ltd and is currently in Phase 3 clinical trials for rabies prevention.