Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Sinovac rabies vaccine · 2 trials · 1 indication
| Arm | Type | Description |
|---|---|---|
| Sinovac rabies vaccine - Batch 1 | EXPERIMENTAL | Subjects will be randomly assigned to receive 5 doses of Sinovac rabies vaccine (Batch 1) on Day 0,3,7,14,28 |
| Sinovac rabies vaccine - Batch 2 | EXPERIMENTAL | Subjects will be randomly assigned to receive 5 doses of Sinovac rabies vaccine (Batch 2) on Day 0,3,7,14,28 |
| Sinovac rabies vaccine - Batch 3 | EXPERIMENTAL | Subjects will be randomly assigned to receive 5 doses of Sinovac rabies vaccine (Batch 3) on Day 0,3,7,14,28 |
| Sinovac rabies vaccine - 5 doses | EXPERIMENTAL | Subjects will be randomly assigned to receive 5 doses of Sinovac rabies vaccine on Day 0,3,7,14,28 |
| Sinovac rabies vaccine - 4-1 doses | EXPERIMENTAL | Subjects will be randomly assigned to receive 4 doses of Sinovac rabies vaccine on Day 0,3,7,14 |
| Sinovac rabies vaccine - 4-2 doses | EXPERIMENTAL | Subjects will be randomly assigned to receive 4 doses of Sinovac rabies vaccine on Day 0,3,7,28 |
| Marketed rabies vaccine - 5 doses | ACTIVE_COMPARATOR | Subjects will be randomly assigned to receive 5 doses of a marketed rabies vaccine in China on Day 0,3,7,14,28 |
| Name | Type | Description |
|---|---|---|
| Sinovac rabies vaccine | BIOLOGICAL | Three batchs of Rabies Vaccine (Serum-free Vero Cell), Freeze-dried using five doses of PEP schedules |
| Marketed rabies vaccine | BIOLOGICAL | A markted Rabies Vaccine using 5 doses of PEP schedules |
Inclusion Criteria: 1. Participants are able to understand and voluntarily sign the Informed Consent Form; 2. Able to provide legal identity documents; 3. Age 18 to 45 years; 4. Stable health status (defined as stable underlying disease status within 3 months prior to enrollment, i.e., no change in...