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Oxcarbazepine

Phase 3

Partial Epilepsy | Small molecule | Neurology |Supernus Pharmaceuticals, Inc.|Last Updated: May 31, 2017

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment214

FDA Designations

No designations recorded

Clinical trial landscape

Oxcarbazepine · 1 trial · 1 indication

Phase 3 1
NCT00908349Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial EpilepsyPartial Epilepsy
COMPLETED214 Analytics
PHASE3COMPLETED
Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial Epilepsy
Partial EpilepsyUnlock trial analytics

Study Endpoints

Primary Endpoints

Percent Change in Seizure Rate
one year

Measured as change from baseline to end of study

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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Oxcarbazepine XROTHEROpen Label Study

Interventions

NameTypeDescription
Oxcarbazepine XRDRUGOpen Label Study
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Eligibility Criteria

Age Range18 Years to 66 Years
SexALL
Healthy VolunteersNo
Study Sites58

Inclusion Criteria 1. Able to provide written informed consent and agree to comply with study procedures. 2. Male or female aged 18 to 66 years, inclusive. 3. Successful completion of the 804P301 study. 4. Sexually active women, unless surgically sterile (at least 6 months prior to Study Medication...

Countries:United StatesBulgariaCanadaCroatiaMexicoPolandRomaniaRussia
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Frequently asked questions about Oxcarbazepine

What is Oxcarbazepine used for?

Oxcarbazepine is an investigational small molecule being developed as an adjunctive therapy for patients with refractory partial epilepsy. It is designed for use in adults aged 18 years and older. The drug is currently in Phase 3 clinical development and has not been approved by the FDA.

Who makes Oxcarbazepine?

Oxcarbazepine is being developed by Supernus Pharmaceuticals, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol SUPN. The company is conducting clinical trials to evaluate the safety and tolerability of this drug as an add-on treatment for partial epilepsy.

What phase is Oxcarbazepine in?

Oxcarbazepine is in Phase 3 clinical development. A Phase 3 trial has been completed to assess its safety and tolerability as adjunctive therapy in subjects with refractory partial epilepsy. The drug remains investigational and is not yet approved for commercial use.

What clinical trials is Oxcarbazepine in?

Oxcarbazepine has one completed Phase 3 clinical trial, registered as NCT00908349. The study evaluated the safety and tolerability of OXC XR as adjunctive therapy in 214 subjects with refractory partial epilepsy. The trial was conducted across multiple countries, including the United States, Bulgaria, Canada, Croatia, Mexico, Poland, Romania, and Russia.

Is Oxcarbazepine FDA approved?

Oxcarbazepine is not FDA approved. It is an investigational drug currently in Phase 3 clinical development for the treatment of partial epilepsy. A completed Phase 3 trial has evaluated its safety and tolerability, but the drug has not yet received regulatory approval.