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Oxcarbazepine

Phase 3

Partial Epilepsy | Small molecule | Neurology |Supernus Pharmaceuticals, Inc.|Last Updated: May 31, 2017

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment214
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00908349Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial EpilepsyPHASE3 COMPLETED 214Jun 1, 2009Nov 1, 2011May 31, 201758 United States, Bulgaria +6
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Study Endpoints
Primary Endpoints
Percent Change in Seizure Rate
one year

Measured as change from baseline to end of study

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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Oxcarbazepine XROTHEROpen Label Study
Interventions
NameTypeDescription
Oxcarbazepine XRDRUGOpen Label Study
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Eligibility Criteria
Age Range18 Years — 66 Years
SexALL
Healthy VolunteersNo
Study Sites58

Inclusion Criteria 1. Able to provide written informed consent and agree to comply with study procedures. 2. Male or female aged 18 to 66 years, inclusive. 3. Successful completion of the 804P301 study. 4. Sexually active women, unless surgically sterile (at least 6 months prior to Study Medication...

Countries:United StatesBulgariaCanadaCroatiaMexicoPolandRomaniaRussia
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