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pristinamycin · 1 trial · 1 indication
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | - |
| 2 | ACTIVE_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| pristinamycin | DRUG | 50 mg/kg/d in 2 doses for children, and 1g twice daily in adults for 4 days |
| amoxicillin | DRUG | 50 mg/kg/d in 2 doses in children and 1 g twice daily in adults for 6 days |
Inclusion Criteria: * subjects of both sexes * aged between 6 and 25 years, * weight : ≥ 20kg * with suspected GAS-induced tonsillitis (erythema and/or exudate of the pharynx and/or tonsils with oropharyngeal pain and/or odynophagia, fever ³ 38°C, appreciable satellite adenopathy) * confirmation by...
Pristinamycin is an investigational small molecule being studied for the treatment of tonsillitis, specifically tonsillitis induced by Streptococcus in children. It is in Phase 3 clinical development and has not been approved by regulatory authorities.
Pristinamycin is being developed by Sanofi, a multinational pharmaceutical company traded on the stock exchange under the ticker symbol SNY. The company is conducting clinical trials to evaluate the drug's efficacy and safety for the treatment of tonsillitis.
Pristinamycin is in Phase 3 clinical development. It is an investigational drug, meaning it has not yet received regulatory approval and is still undergoing clinical trials to assess its safety and efficacy for the treatment of tonsillitis.
Pristinamycin has one completed Phase 3 clinical trial registered under NCT00393744. This trial, titled 'Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children,' enrolled 395 participants in France and included children aged 6 years and older.
No, pristinamycin is not the same as amoxicillin. Pristinamycin is an investigational drug being studied as a potential treatment for tonsillitis, while amoxicillin is an established antibiotic used as an active comparator in clinical trials. The two drugs have different mechanisms of action and chemical structures.