Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00393744 | Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children | PHASE3 | COMPLETED | 395 | — | — | Oct 1, 2006 | - | Mar 17, 2009 | 1 | France |
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | - |
| 2 | ACTIVE_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| pristinamycin | DRUG | 50 mg/kg/d in 2 doses for children, and 1g twice daily in adults for 4 days |
| amoxicillin | DRUG | 50 mg/kg/d in 2 doses in children and 1 g twice daily in adults for 6 days |
Inclusion Criteria: * subjects of both sexes * aged between 6 and 25 years, * weight : ≥ 20kg * with suspected GAS-induced tonsillitis (erythema and/or exudate of the pharynx and/or tonsils with oropharyngeal pain and/or odynophagia, fever ³ 38°C, appreciable satellite adenopathy) * confirmation by...