Recent Updates
Recently added Catalysts

iBGStar, Traditional Glucometer

Phase 3

Diabetes Mellitus | Unknown | Metabolic |Sanofi|Last Updated: Apr 14, 2016

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials1
Total Enrollment186
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT02073188Comparative Study of a Smartphone-Linked Self-Monitoring System Versus a Traditional One for Improving Metabolic Control and Compliance to Self-Monitoring of Blood GlucosePHASE3 COMPLETED 186Jun 1, 2012Sep 1, 2014Apr 14, 20161 Italy
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Change in HbA1c levels from baseline
baseline to six months
Proportion of participants performing at least 30% of the recommended Self-Monitoring Blood Glucose tests after 6 months from randomization
at 6 months
Secondary Endpoints
Percentage of participants with HbA1c ≤7.5%
at 6 months and 12 months
Average number of recommended Self-Monitoring Blood Glucose tests daily, weekly, and monthly
at 6 months and 12 months
Mean fasting plasma glucose (FPG) and postprandial glucose (PPG)
at 6 months and 12 months
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
Treatment Arms
ArmTypeDescription
iBGStar (Group A)EXPERIMENTALSelf-Monitoring Blood Glucose will be managed with iBGStar and iBGStar Diabetes Manager Application (App) uploaded on iPhone for all duration of the study (6 months of experimental phase plus 6-months of observational phase). In the first 3 months, the patients in Group A will send their glycemic test values and notes by mail to the physician through Diabetes Manager App every 2 weeks. Afterwards until the visit V2 (six months), the patients in Group A will send their glycemic test values and notes by mail monthly. 9 reports in total.
Traditional Glucometer (Group B)ACTIVE_COMPARATORSelf-Monitoring Blood Glucose will be managed with a traditional glucometer according to usual care for the first 6 months (experimental phase). In the 6 months post-trial follow-up (observational phase), Self-Monitoring Blood Glucose will be managed with iBGStar and iBGStar Diabetes Manager App.
Interventions
NameTypeDescription
iBGStarDEVICE -
Traditional GlucometerDEVICE -
Unlock Study Design Details
Eligibility Criteria
Age Range14 Years — 24 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Type 1 diabetes * Males and females * Age between 14-24 years * Any diabetes duration * Cared for by the diabetes center for at least 1 year * HbA1c ≥ 8% * Basal bolus treatment (any insulin) * Poor compliance with Self-Monitoring of Blood Glucose (less than 30% of the recomme...

Countries:Italy
Unlock Eligibility Criteria