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hyaluronate

Phase 3

Osteoarthritis of Shoulder | Small molecule | Musculoskeletal |Sanofi|Trials Updated: Jan 11, 2011

hyaluronate target and mechanism

ModalitySmall molecule

Also known as sodium hyaluronate

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment602

FDA Designations

No designations recorded

hyaluronate clinical trials

hyaluronate · 1 trial · 1 indication

Phase 3 1
NCT00377624HUPS: Hyalgan Use in Painful ShoulderOsteoarthritis of Shoulder
COMPLETED602 Analytics
PHASE3COMPLETED
HUPS: Hyalgan Use in Painful Shoulder
Osteoarthritis of ShoulderUnlock trial analytics

Study Endpoints

Primary Endpoints

Improvement in shoulder pain on movement in previous 24 hours, based upon 100 mm VAS score up to 3 months after baseline for the 3 i.a. and 5 i.a. sodium hyaluronate injections compared to PB-Saline control

Secondary Endpoints

Maintenance or improvement from baseline in shoulder pain on movement in previous 24 hours based upon 100 mm VAS score up to 6 months after baseline of
sodium hyaluronate treated patients compared to PB-Saline.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
sodium hyaluronateDRUG -
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Eligibility Criteria

Age Range35 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

The following information on clinical trials is provided for information purposes only to allow patients and physicians to have an initial discussion about the trial. This information is not intended to be complete information about the trial, to contain all considerations that may be relevant to po...

Countries:United States
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Frequently asked questions about hyaluronate

What is hyaluronate used for?

Hyaluronate is being studied for osteoarthritis of the shoulder. Sanofi is developing it as a Phase 3 treatment in the musculoskeletal therapeutic area. The completed Phase 3 trial HUPS evaluated hyaluronate in patients with painful shoulder osteoarthritis, enrolling 602 participants in the United States.

Who makes hyaluronate?

Hyaluronate is developed by Sanofi, which trades under the ticker SNY. Sanofi is the sponsor of the Phase 3 clinical program evaluating hyaluronate for osteoarthritis of the shoulder.

What phase is hyaluronate in?

Hyaluronate is in Phase 3 development. One Phase 3 trial has been completed, and no trials are currently active. The completed study, HUPS, was a randomized, double-blind trial that enrolled 602 participants with osteoarthritis of the shoulder.

What clinical trials is hyaluronate in?

Hyaluronate has been evaluated in one Phase 3 clinical trial, NCT00377624, titled HUPS: Hyalgan Use in Painful Shoulder. The trial studied osteoarthritis of the shoulder, enrolled 602 participants, was randomized and double-blind, and has been completed. It was conducted in the United States.

Is hyaluronate the same as sodium hyaluronate?

Yes, hyaluronate is also known as sodium hyaluronate. Both names refer to the same Sanofi compound being developed for osteoarthritis of the shoulder.