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anti-thymocyte globulin

Phase 2

Myelodysplastic Syndromes | Monoclonal antibody | Hematology |Sanofi|Last Updated: Jan 27, 2021

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedUNCONTROLLED
Total Trials1
Total Enrollment -
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00017550Antithymocyte Globulin Compared With Supportive Care in Treating Patients With Myelodysplastic SyndromePHASE2 COMPLETED -Sep 1, 2000Nov 1, 2003Jan 27, 202128 United States, Canada
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
PurposeTREATMENT
Interventions
NameTypeDescription
anti-thymocyte globulinBIOLOGICAL -
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Eligibility Criteria
Age Range18 Years — 120 Years
SexALL
Healthy VolunteersNo
Study Sites28

DISEASE CHARACTERISTICS: * Histologically or cytologically confirmed early myelodysplastic syndrome (MDS) with less than 10% bone marrow blasts * Refractory anemia (RA) * RA with excess blasts (RAEB) * Hypocellular myelodysplasia * Low or intermediate-1 prognostic risk * Transfusion-dependen...

Countries:United StatesCanada
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Competitive Landscape -Myelodysplastic Syndromes 76 trials
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