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Vasopressin V2 Receptor Antagonist

Phase 2

Chronic Heart Failure | Small molecule | Cardiovascular |Sanofi|Last Updated: Jun 17, 2008

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment338

FDA Designations

No designations recorded

Clinical trial landscape

Vasopressin V2 Receptor Antagonist · 1 trial · 1 indication

Phase 2 1
NCT00032747Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT).Chronic Heart Failure
COMPLETED338 Analytics
PHASE2COMPLETED
Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT).
Chronic Heart FailureUnlock trial analytics

Study Endpoints

Primary Endpoints

Clinical status at day 120.

Secondary Endpoints

NYHA functional class, left ventricular ejection fraction, global assessment,serum sodium concentration.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
Vasopressin V2 Receptor AntagonistDRUG -
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Eligibility Criteria

Age Range18 Years to 80 Years
SexALL
Healthy VolunteersNo
Study Sites9

* Men or women with chronic heart failure (NYHA Class IIIB and IV). * Women must be post-menopausal or surgically sterilized; they cannot be pregnant or nursing. * Age 21 to 80 years. * Chronic heart failure of at least 3 months duration. For 2 months prior to screening, patients must have had sympt...

Countries:United StatesCanadaUnited Kingdom
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Frequently asked questions about Vasopressin V2 Receptor Antagonist

What is Vasopressin V2 Receptor Antagonist used for in chronic heart failure?

Vasopressin V2 Receptor Antagonist is an investigational small molecule being studied for the treatment of chronic heart failure. It is a vasopressin V2 receptor antagonist, which means it blocks the action of vasopressin on V2 receptors. The drug is currently in Phase 2 clinical development.

Who makes Vasopressin V2 Receptor Antagonist?

Sanofi (ticker: SNY) is developing Vasopressin V2 Receptor Antagonist. The drug is an investigational small molecule in Phase 2 clinical development for chronic heart failure, a cardiovascular condition.

What phase is Vasopressin V2 Receptor Antagonist in?

Vasopressin V2 Receptor Antagonist is in Phase 2 clinical development. It is an investigational drug for chronic heart failure and has not been approved by regulatory authorities. One Phase 2 clinical trial has been completed.

What clinical trials is Vasopressin V2 Receptor Antagonist in?

Vasopressin V2 Receptor Antagonist has one completed Phase 2 clinical trial, NCT00032747, titled "Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT)." The trial enrolled 338 participants with chronic heart failure in the United States, Canada, and the United Kingdom.

What does Vasopressin V2 Receptor Antagonist target?

Vasopressin V2 Receptor Antagonist targets the vasopressin V2 receptor. By blocking this receptor, the drug is designed to counteract the effects of vasopressin, which is relevant to its potential use in chronic heart failure. The drug is a small molecule in Phase 2 development.

Is Vasopressin V2 Receptor Antagonist the same as AQUAVIT?

Vasopressin V2 Receptor Antagonist is the drug being studied in the AQUAVIT clinical trial, but AQUAVIT is the name of the trial, not an alternative name for the drug. The trial is titled "Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT)."