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SSR149744C

Phase 2

Arrhythmia | Small molecule | Cardiovascular |Sanofi|Last Updated: May 8, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment153

FDA Designations

No designations recorded

Clinical trial landscape

SSR149744C · 1 trial · 3 indications

Phase 2 1
NCT00232297Double Blind Placebo Controlled Dose Ranging Study of the Efficacy and Safety of SSR149744c 100 or 300 mg for the Prevention of ventrICular ARrhythmia-triggered Icd interventiOnSArrhythmia
COMPLETED153 Analytics
PHASE2COMPLETED
Double Blind Placebo Controlled Dose Ranging Study of the Efficacy and Safety of SSR149744c 100 or 300 mg for the Prevention of ventrICular ARrhythmia-triggered Icd interventiOnS
ArrhythmiaUnlock trial analytics

Study Endpoints

Primary Endpoints

Primary endpoint is time to all ventricular tachycardia or ventricular fibrillation arrhythmia leading to any ICD intervention (anti-tachycardia pacing or ICD shock).

Secondary Endpoints

Time to all arrhythmia episodes leading to at least one documented ICD shock.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
SSR149744CDRUG -
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Eligibility Criteria

Age Range21 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites8

Inclusion Criteria: * Patient with an ICD implanted during the previous year for documented spontaneous life-threatening ventricular arrhythmia OR implanted with an ICD and with at least one appropriate ICD therapy (shock or anti-tachycardia pacing) for ventricular tachycardia or ventricular fibril...

Countries:United StatesBelgiumCanadaCzechiaGermanyItalyNetherlandsSwitzerland
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Competitive Landscape -Arrhythmia 12 trials

Frequently asked questions about SSR149744C

What is SSR149744C used for?

SSR149744C is an investigational small molecule being studied for the prevention of ventricular arrhythmias, including ventricular tachycardia and ventricular fibrillation, in patients with arrhythmia. It is being developed as a potential treatment to reduce arrhythmia-triggered ICD interventions.

What does SSR149744C target?

SSR149744C is a small molecule, but its specific molecular target has not been disclosed. It is being investigated for its antiarrhythmic properties in the cardiovascular therapeutic area, with the goal of preventing ventricular arrhythmias.

Who makes SSR149744C?

SSR149744C is being developed by Sanofi, a global biopharmaceutical company listed on the stock exchange under the ticker SNY. Sanofi is conducting clinical research to evaluate the safety and efficacy of this investigational drug for arrhythmia.

What phase is SSR149744C in?

SSR149744C is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still being studied for safety and efficacy in patients with ventricular arrhythmias.

What clinical trials is SSR149744C in?

SSR149744C has one completed Phase 2 clinical trial, identified as NCT00232297. This was a double-blind, placebo-controlled, dose-ranging study evaluating 100 mg and 300 mg doses of SSR149744C for the prevention of ventricular arrhythmia-triggered ICD interventions, enrolling 153 patients across multiple countries.

Is SSR149744C the same as another drug?

SSR149744C is the investigational code name for this drug. No alternative brand names or other designations have been disclosed for this compound in the available information.