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SL650472, Clopidogrel

Phase 2

Intermittent Claudication | Small molecule | Cardiovascular |Sanofi|Last Updated: Dec 19, 2008

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment599

FDA Designations

No designations recorded

Clinical trial landscape

SL650472, Clopidogrel · 1 trial · 1 indication

Phase 2 1
NCT00300339Mixed Antagonist of Serotonin for Claudication Optimal TherapyIntermittent Claudication
COMPLETED599 Analytics
PHASE2COMPLETED
Mixed Antagonist of Serotonin for Claudication Optimal Therapy
Intermittent ClaudicationUnlock trial analytics

Study Endpoints

Primary Endpoints

Primary: percent change in initial claudication distance (ICD) measured at the 24-week test, compared with that at baseline

Secondary Endpoints

Success, defined as an improvement of > 50% in ICD at the 24-week test compared with that at baseline
Percent change in absolute claudication distance (ACD) at the 24-week test, compared with that at baseline,
Functional status / quality of life (QoL) using WIQ and MOS SF-36 questionnaires,
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
SL650472, ClopidogrelDRUG -
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Eligibility Criteria

Age Range40 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites9

Inclusion Criteria: * 1\. Patient with stable symptoms of intermittent claudication of the lower extremities, secondary to chronic occlusive arterial disease from atherosclerosis origin (symptoms present for 6 months or longer and not significantly changed within the past 3 months); * 2\. ICD of 30...

Countries:United StatesBelgiumCanadaCzechiaGermanyMexicoRussiaSwedenUkraine
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Frequently asked questions about SL650472, Clopidogrel

What is SL650472 used for?

SL650472 is an investigational small molecule being studied for the treatment of intermittent claudication, a condition characterized by leg pain due to inadequate blood flow during exercise. It is currently in Phase 2 clinical development.

Who makes SL650472?

SL650472 is being developed by Sanofi, a multinational pharmaceutical company. Sanofi's stock is traded under the ticker symbol SNY.

What phase is SL650472 in?

SL650472 is in Phase 2 clinical development. It has completed one Phase 2 trial, which was a randomized, double-blind study. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is SL650472 in?

SL650472 has one completed clinical trial registered under NCT00300339, titled "Mixed Antagonist of Serotonin for Claudication Optimal Therapy." This Phase 2 study enrolled 599 participants with intermittent claudication across multiple countries.

Is SL650472 the same as Clopidogrel?

Yes, SL650472 is also known as Clopidogrel. This alternative name may be used in medical literature and clinical contexts, and both names refer to the same investigational drug.