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Purified inactivated rabies vaccine, serum free · 1 trial · 2 indications
Rabies virus neutralizing antibody (RVNA) titer as determined by rapid fluorescent focus inhibition test (RFFIT)
| Arm | Type | Description |
|---|---|---|
| VRVg Vaccine Group 1 | EXPERIMENTAL | Participants aged 18 years or older will receive Purified Vero Rabies Vaccine Serum Free (VRVg) |
| VRVg Vaccine Group 2 | EXPERIMENTAL | Participants aged 10 to 17 years will receive Purified Vero Rabies Vaccine Serum Free (VRVg) |
| Verorab Vaccine Group 1 | ACTIVE_COMPARATOR | Participants aged 18 years or older will receive Verorab Vaccine |
| Verorab Vaccine Group 2 | ACTIVE_COMPARATOR | Participants aged 10 to 17 years will receive Verorab Vaccine |
| Name | Type | Description |
|---|---|---|
| Purified inactivated rabies vaccine, serum free | BIOLOGICAL | 0.5 mL, Intramuscular |
| Purified Vero Rabies Vaccine | BIOLOGICAL | 0.5 mL, Intramuscular |
Inclusion Criteria: Adults (≥ 18 years) * Aged ≥ 18 years on the day of inclusion * Informed consent form has been signed and dated * Able to attend all scheduled visits and to comply with all trial procedures * For a woman of childbearing potential, use of an effective method of contraception or ...
Purified inactivated rabies vaccine, serum free is an investigational vaccine being developed for rabies prevention. It is designed to protect against rabies virus infection. The vaccine is currently in Phase 3 clinical development and is being studied in healthy volunteers aged 10 years and older.
Purified inactivated rabies vaccine, serum free is being developed by Sanofi, a company traded on the stock exchange under the ticker SNY. Sanofi is conducting clinical trials to evaluate the vaccine's safety and efficacy for rabies prevention.
Purified inactivated rabies vaccine, serum free is in Phase 3 clinical development. It is an investigational vaccine and has not been approved by regulatory authorities. The Phase 3 trial has been completed, and the vaccine remains under evaluation for rabies prevention.
Purified inactivated rabies vaccine, serum free has one completed Phase 3 clinical trial registered as NCT01339312. This study compared the vaccine with a reference purified Vero rabies vaccine in 816 participants in China. The trial was randomized, double-blind, and active-controlled, enrolling healthy volunteers aged 10 years and older.
Purified inactivated rabies vaccine, serum free is a vaccine developed using a serum-free manufacturing process. In clinical trials, it has been compared with a reference purified Vero rabies vaccine. The vaccine is being studied as a potential alternative to existing rabies vaccines, but it is not the same as the reference vaccine.