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Lactic Acid · 37 trials · 2 indications
Patient's questionnaire will be completed at V1, V2 and V4. Reduction of vaginal odor, increase in the moisture area, and perception about some items like foam, facility of rinsing, final touch of the mucosa, final fragrance, and cleaning sensation will be rated on a 5-point scale.
| Arm | Type | Description |
|---|---|---|
| Dermacyd (different fragrances) | EXPERIMENTAL | Day 1 until 30: Investigational Product (Dermacyd) Day 31 until 37: wash-out Day 38 until 67: Glycerine Vegetal Soap Granado Traditional |
| Glycerine Vegetal Soap Granado Traditional | ACTIVE_COMPARATOR | Day 1 until 30: Glycerine Vegetal Soap Granado Traditional Day 31 until 37: wash-out Day 38 until 67: Investigational Product (Dermacyd) |
| Dermacyd Silver Frutal (Lactic Acid) | EXPERIMENTAL | Dermacyd Silver Frutal (Lactic Acid) sample will be applied like a curative. Physiologic solution and mineral oil will be also used as a control sample. |
| Dermacyd PH_DESILSTY_FR (Lactic Acid) | EXPERIMENTAL | Dermacyd PH\_DESILSTY\_FR (Lactic Acid) sample will be applied like a curative. Physiologic solution and mineral oil will be also used as a control sample. |
| Dermacyd PH_DESILSTY_FL (Lactic Acid) | EXPERIMENTAL | Dermacyd PH\_DESILSTY\_FL (Lactic Acid) sample will be applied like a curative. Physiologic solution and mineral oil will be also used as a control sample |
| Dermacyd Silver Floral (Lactic Acid) | EXPERIMENTAL | Dermacyd Silver Floral (Lactic Acid) sample will be applied like a curative. Physiologic solution and mineral oil will be also used as a control sample. |
| 1 | EXPERIMENTAL | Lactic Acid (Dermacyd Femina) |
| I | EXPERIMENTAL | - |
| 2 | PLACEBO_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| LACTIC ACID (Dermacid) | DRUG | Route of administration: local |
| Glycerine Vegetal Soap Granado Traditional | DRUG | Route of administration: local |
| LACTIC ACID(ND) | DRUG | Dermacyd Silver Frutal (Lactic Acid) sample will be applied like a curative for 21 consecutive days. |
| Lactic Acid | DRUG | Lactic Acid (Dermacyd Femina) |
| Lactic Acid (Dermacyd PH_DETINBACK Tangerine Mix) | DRUG | Lactic Acid |
| Lactic Acid (Dermacyd PH_DETINLYN Tangerine Mix) | DRUG | Lactic Acid (Dermacyd PH\_DETINLYN Tangerine Mix) |
| Lactic acid (Dermacyd Femina) | DRUG | - |
| Lactic acid (Dermacyd Femina Delicata) | DRUG | - |
| Distilled water | OTHER | Application of patches containing distilled water for 24 hours |
Inclusion criteria: * Perfect mucosa in the product analysis region * Volunteers with active sexual life: normal Papanicolau test performed less than one year is mandatory * Bacterioscopy describing the vaginal flora * Negative Trichomonas vaginalis test * Negative Whiff test * Willingness in using...
Lactic Acid is an investigational small molecule being developed by Sanofi for healthy hygiene applications. It is currently in Phase 3 clinical trials, with studies evaluating dermatological compatibility and photo evaluation of products such as Dermacyd Delicata and Dermacyd Tina Gel in healthy female volunteers.
Sanofi (ticker: SNY) is developing Lactic Acid. The company is conducting Phase 3 clinical trials to evaluate the product's dermatological compatibility and photo effects in healthy volunteers, with studies completed in Brazil.
Lactic Acid is in Phase 3 clinical development. It is an investigational product, not yet approved, with 30 completed trials and no active trials currently enrolling. All trials have been completed, involving a total of 1,458 participants.
Lactic Acid has completed 30 Phase 3 trials, including NCT00668460, NCT00668486, NCT00668629, and NCT00669058. These studies evaluated dermatological compatibility and photo effects of Dermacyd products in healthy female volunteers aged 18 and older in Brazil.
Lactic Acid is the active ingredient in Dermacyd products, which are being tested in clinical trials. The trials evaluate Dermacyd Delicata and Dermacyd Tina Gel formulations containing Lactic Acid for healthy hygiene use.