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Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC

Phase 2

Diphtheria | Monoclonal antibody | Infectious Disease |Sanofi|Last Updated: Jan 14, 2014

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDDMC
Total Trials1
Total Enrollment460

FDA Designations

No designations recorded

Clinical trial landscape

Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC · 1 trial · 5 indications

Phase 2 1
NCT00362427Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar®Diphtheria
COMPLETED460 Analytics
PHASE2COMPLETED
Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar®
DiphtheriaUnlock trial analytics

Study Endpoints

Primary Endpoints

To provide information concerning the immune response of subjects that received PR5I concomitantly with Prevnar
14 Months
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
Group AEXPERIMENTAL -
Group BEXPERIMENTAL -
Group CACTIVE_COMPARATOR -

Interventions

NameTypeDescription
Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPCBIOLOGICAL0.5 mL, 4 doses, IM
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Eligibility Criteria

Age Range42 Days to 89 Days
SexALL
Healthy VolunteersYes
Study Sites8

Inclusion Criteria: * Infants aged 42 to 89 days inclusive on the day of inclusion. * Born at full term of pregnancy (\>37 weeks). * Informed consent form signed by the parent(s) or legally authorized representative. * Able to attend all scheduled visits and to comply with the study procedures. * P...

Countries:Canada
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Frequently asked questions about Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC

What is Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC?

Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC is an investigational pediatric combination vaccine developed by Sanofi. It is designed to protect against diphtheria, pertussis, polio, hepatitis B, and tetanus in a single regimen. The vaccine combines diphtheria and tetanus toxoids, acellular pertussis components, inactivated poliovirus, and a hepatitis B component.

What is Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC used for?

Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC is being studied for active immunization against diphtheria, pertussis, polio, hepatitis B, and tetanus in infants and young children. The Phase 2 trial enrolled healthy pediatric participants starting at 42 days of age. It is an investigational combination vaccine and has not been approved for use.

Who makes Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC?

Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC is developed by Sanofi, which trades under the ticker SNY. Sanofi is the sponsor of the clinical program evaluating this pediatric combination vaccine candidate.

What phase is Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC in?

Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC is in Phase 2 clinical development. It is an investigational vaccine and is not FDA approved. The Phase 2 study has been completed, and no active trials of this candidate are currently listed.

What clinical trials is Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC in?

Hybrid 5 component DTaP, Vero IPV, Hep B and PRP-OMPC was evaluated in one completed Phase 2 trial, NCT00362427, titled Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar. The trial enrolled 460 healthy participants in Canada, was randomized and active controlled, and included infants from 42 days of age.