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HP184

Phase 2

Spinal Cord Injury | Small molecule | Neurology |Sanofi|Last Updated: Aug 21, 2008

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment262

FDA Designations

No designations recorded

Clinical trial landscape

HP184 · 1 trial · 1 indication

Phase 2 1
NCT00093275HP184 in Chronic Spinal Cord Injury SubjectsSpinal Cord Injury
COMPLETED262 Analytics
PHASE2COMPLETED
HP184 in Chronic Spinal Cord Injury Subjects
Spinal Cord InjuryUnlock trial analytics

Study Endpoints

Primary Endpoints

Change from baseline in total motor score of American Spinal Injury Association (ASIA) manual motor test at Week 24.

Secondary Endpoints

Safety evaluation.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
HP184DRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria: * Male and female subjects with incomplete (traumatic), chronic (defined as 18 months or more post spinal cord injury) SCI aged 18 to 65 years * CSCI must be categorized in classes C or D in the ASIA impairment scale. (C = Incomplete impairment with motor function preserved belo...

Countries:United StatesAustraliaGermanyIndiaUnited Kingdom
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Frequently asked questions about HP184

What is HP184 used for?

HP184 is an investigational small molecule being developed for the treatment of spinal cord injury. It is intended for patients with chronic spinal cord injury, a neurological condition that can result in loss of motor and sensory function. The drug is currently in clinical development, having completed a Phase 2 trial.

Who makes HP184?

HP184 is being developed by Sanofi, a multinational pharmaceutical company listed on the stock exchange under the ticker symbol SNY. Sanofi is responsible for the research and clinical development of this investigational drug for spinal cord injury.

What phase is HP184 in?

HP184 is in Phase 2 of clinical development. A Phase 2 trial has been completed, but the drug is not yet approved and remains investigational. It is still in the clinical research stage, and further studies may be needed to establish its safety and efficacy.

What clinical trials is HP184 in?

HP184 has one completed clinical trial registered under the identifier NCT00093275. This Phase 2 study, titled 'HP184 in Chronic Spinal Cord Injury Subjects,' enrolled 262 participants across the United States, Australia, Germany, India, and the United Kingdom. The trial was randomized and double-blind.

Is HP184 FDA approved?

HP184 is not FDA approved. It is an investigational drug that has completed a Phase 2 clinical trial for spinal cord injury. The drug is still in clinical development, and its safety and efficacy have not been fully established. Regulatory approval has not been granted.