Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00198822 | Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh | PHASE3 | COMPLETED | 59,666 | — | — | Aug 1, 2001 | Mar 1, 2008 | Mar 7, 2012 | 3 | United States, Bangladesh |
Mortality evaluated on intent-to-treat basis
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | Weekly oral supplement with 7000 µg retinol equivalents from early pregnancy through 12 weeks following termination of pregnancy |
| 2 | EXPERIMENTAL | Weekly oral supplement with 42 mg of beta-carotene from early pregnancy through 12 weeks following termination of pregnancy |
| 3 | PLACEBO_COMPARATOR | Weekly oral supplement with placebo from early pregnancy through 12 weeks following termination of pregnancy |
| Name | Type | Description |
|---|---|---|
| Vitamin A or Beta-Carotene Supplements | DIETARY_SUPPLEMENT | weekly dosage of either 7000 µg retinol equivalents as preformed vitamin A or 42 mg of beta-carotene from 1st trimester of pregnancy through 12 weeks after termination of pregnancy |
Inclusion Criteria: * Married women of reproductive age * First pregnancy during time period of trial Exclusion Criteria: * Premenarchial girls * Married women with a previous pregnancy enrolled into the trial * Previously married women who have moved into the study area * Single women (never mar...