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SER-252

Phase 1

PARKINSON DISEASE (Disorder) | Small molecule | Neurology |AgeX Therapeutics, Inc.|Last Updated: Mar 2, 2026

Target and mechanism

ModalitySmall molecule

Also known as SER-252 (PEOZ-apomorphine)

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment40

FDA Designations

No designations recorded

Clinical trial landscape

SER-252 · 1 trial · 2 indications

Phase 1 1
NCT07422675SAD Study in Patients With Parkinson's Disease and Motor FluctuationsPARKINSON DISEASE (Disorder)
RECRUITING40 Analytics
PHASE1RECRUITING
SAD Study in Patients With Parkinson's Disease and Motor Fluctuations
PARKINSON DISEASE (Disorder)Unlock trial analytics

Study Design & Arms

Interventions

NameTypeDescription
SER-252 (PEOZ-apomorphine)DRUGSER-252 drug product consists of 20mg lyophilized apomorphine equivalent in SER-252 drug substance in a sterile vial for reconstitution with a diluent product containing 15mM acetate buffer at pH 6.0 and 7% trehalose to maintain final pH and isotonicity in the reconstituted product.
enFuseDEVICEThe enFuse® device is a sterile, non-pyrogenic, user-filled, single-use, fixed-dose subcutaneous dose delivery system.
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Frequently asked questions about SER-252

What is SER-252 used for?

SER-252 is an investigational small molecule being developed for Parkinson's disease, specifically for patients with motor fluctuations. It is currently in Phase 1 clinical development and has not been approved by the FDA. The drug is being studied in patients with advanced Parkinson's disease.

How does SER-252 work?

SER-252 is a small molecule therapeutic being developed for Parkinson's disease. The specific molecular target of SER-252 has not been disclosed in available information. It is being studied for its potential to address motor fluctuations in patients with advanced Parkinson's disease.

Who is developing SER-252?

SER-252 is being developed by AgeX Therapeutics, Inc., a biopharmaceutical company. The company is conducting clinical trials to evaluate the safety and efficacy of SER-252 in patients with Parkinson's disease and motor fluctuations.

What phase is SER-252 in?

SER-252 is currently in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The ongoing Phase 1 trial is a single ascending dose study in patients with Parkinson's disease and motor fluctuations.

What clinical trials is SER-252 in?

SER-252 is being evaluated in a Phase 1 clinical trial with the identifier NCT07422675. This is a single ascending dose study in patients with Parkinson's disease and motor fluctuations, with an enrollment of 40 participants. The trial is currently recruiting and is uncontrolled.

Is SER-252 the same as PEOZ-apomorphine?

Yes, SER-252 is also known as SER-252 (PEOZ-apomorphine). This alternative name may be used in some contexts to refer to the same investigational drug being developed by AgeX Therapeutics for Parkinson's disease.