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HEC74647

Phase 1

Chronic Hepatitis C | Small molecule | Infectious Disease |Sunshine Biopharma Inc.|Last Updated: Nov 5, 2020

Success Probability

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Market & Valuation

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Trial Design

CONTROLLED
Total Trials1
Total Enrollment28

FDA Designations

No designations recorded

Clinical trial landscape

HEC74647 · 1 trial · 1 indication

Phase 1 1
NCT04232514Drug-drug Interaction Study Between HEC74647PA Capsule and HEC110114 Tablets in Healthy SubjectsChronic Hepatitis C
COMPLETED28 Analytics
PHASE1COMPLETED
Drug-drug Interaction Study Between HEC74647PA Capsule and HEC110114 Tablets in Healthy Subjects
Chronic Hepatitis CUnlock trial analytics

Study Endpoints

Primary Endpoints

Adverse Events
From Days 1-26

Incidence of adverse events

Cmax
Day 7-12 and Day 19-26

Maximum plasma concentration of study drugs

AUC
Day 7-12 and Day 19-26

Maximum plasma concentration of study drugs

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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Part AEXPERIMENTALSubjects will receive HEC74647 on Day 1\~7 and Day13\~19, co-administration with HEC110114 on Day13\~19.
Part BEXPERIMENTALSubjects will receive HEC110114 on Day 1\~7 and Day13\~19, co-administration with HEC74647 on Day13\~19.

Interventions

NameTypeDescription
HEC74647DRUGAdministered HEC74647 200 mg orally once daily in fed state
HEC110114DRUGAdministered HEC110114 800 mg orally once daily in fed state
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Eligibility Criteria

Age Range18 Years to 45 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Sign the informed consent form before the trial and fully understand the contents of the trial, the process and possible adverse reactions. * Be able to complete the study according to the trail protocol. * Subjects (including partners) have no pregnancy plan within 3 months a...

Countries:China
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Frequently asked questions about HEC74647

What is HEC74647 used for?

HEC74647 is an investigational small molecule being developed for the treatment of chronic Hepatitis C. It is currently in Phase 1 clinical development and is not yet approved by regulatory authorities. The drug is being studied as a potential therapy for this infectious disease.

Who makes HEC74647?

HEC74647 is being developed by Sunshine Biopharma Inc., a biopharmaceutical company traded on the stock exchange under the ticker symbol SBFM. The company is advancing this small molecule through clinical development for the treatment of chronic Hepatitis C.

What phase is HEC74647 in?

HEC74647 is currently in Phase 1 clinical development. It is an investigational drug and has not yet received regulatory approval. The Phase 1 trial has been completed, and the drug remains in the early stages of clinical testing for chronic Hepatitis C.

What clinical trials is HEC74647 in?

HEC74647 has one completed Phase 1 clinical trial registered under NCT04232514. This study was a drug-drug interaction trial between HEC74647PA capsules and HEC110114 tablets in healthy subjects. The trial enrolled 28 participants and was conducted in China.

Is HEC74647 FDA approved?

HEC74647 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development for the treatment of chronic Hepatitis C. The drug has not yet completed the clinical trials required for regulatory approval and remains under investigation.