Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Also known as Clifutinib with fed state
Clifutinib with · 1 trial · 1 indication
Pharmacokinetics parameters in fasting state and fed state
Pharmacokinetics parameters in fasting state and fed state
| Arm | Type | Description |
|---|---|---|
| Fed states in healthy subjects | EXPERIMENTAL | A single 40mg dose of Clifutinib administered in a fed state. |
| Fasted states in healthy subjects | EXPERIMENTAL | A single 40mg dose of Clifutinib administered in a Fasted state. |
| Name | Type | Description |
|---|---|---|
| Clifutinib with fed state | DRUG | 40 mg Clifutinib with food |
| Clifutinib with fasted state | DRUG | 40 mg Clifutinib without food |
Inclusion Criteria: * Healthy subjects (male or female), age greater than or equal to 18 years and less than or equal to 45 years; * Weight ≥50 kg (≥45 kg for female), and have a body mass index (BMI) between 18 and 28 (including 18 and 28) at screening; * Physical examination, clinical laboratory ...