Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
2% Chlorhexidine gluconate cloth · 1 trial · 1 indication
incidence of bacteremia comparing those in treatment and control groups
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | Daily bathing with 2% chlorhexidine gluconate |
| 2 | NO_INTERVENTION | Standard bathing with soap and water basin or disposable cloth |
| Name | Type | Description |
|---|---|---|
| 2% Chlorhexidine gluconate cloth | DRUG | Daily bathing |
Inclusion Criteria: * Patients in pediatric intensive care unit Exclusion Criteria: * Patients with a history of an allergic reaction to chlorhexidine * Patients less than 2 months of age * Patients with severe skin disease or burn * Patients with an indwelling epidural catheter or lumbar drain
2% Chlorhexidine gluconate cloth is used for nosocomial infections, which are infections acquired in a healthcare setting. It is being studied as a bathing intervention to reduce these infections in pediatric intensive care unit patients. The drug is in Phase 2 clinical development and is not yet approved.
Sage Therapeutics, Inc. (NASDAQ: SAGE) is developing 2% Chlorhexidine gluconate cloth. The company is conducting clinical research on this product for the prevention of nosocomial infections in pediatric intensive care unit patients.
2% Chlorhexidine gluconate cloth is in Phase 2 clinical development. It is an investigational product and has not been approved by regulatory authorities. One Phase 2 trial has been completed, and the product is not currently in active clinical trials.
2% Chlorhexidine gluconate cloth has one completed clinical trial, NCT00549393, titled "Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit." This Phase 2 trial enrolled 5,659 participants in the United States and was not blinded.
2% Chlorhexidine gluconate cloth is a small molecule antiseptic. It works by reducing bacteria on the skin through bathing, which may help prevent nosocomial infections in hospitalized patients. The cloth delivers chlorhexidine gluconate to the skin surface during patient bathing.
2% Chlorhexidine gluconate cloth is not FDA approved. It is an investigational product currently in Phase 2 clinical development. The completed trial NCT00549393 studied its use in pediatric intensive care unit patients, but the product has not received regulatory approval.