Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Also known as [ 14C]-labeled RO7269162
labeled RO7269162 · 1 trial · 1 indication
| Arm | Type | Description |
|---|---|---|
| Arm 1 | EXPERIMENTAL | Participants will receive one oral dose of \[14C\]-labeled RO7269162 on Day 1. |
| Name | Type | Description |
|---|---|---|
| [ 14C]-labeled RO7269162 | DRUG | Participants will receive one oral dose of \[14C\]-labeled RO7269162. |
Inclusion Criteria: * Male participants aged 35 to 64 years of age (inclusive), at screening * Body weight ≥ 50 kg and body mass index within the range 18 to 30 kg/m2 (inclusive), at screening * Male participants who, for 3 months after dosing of \[14C\]-RO7269162, agree to: remain abstinent (refra...
RO7269162 is an investigational small molecule developed by Roche Holding AG. It is in Phase 1 clinical development, and its intended therapeutic indication has not been disclosed. A carbon-14 labeled version, [14C]-labeled RO7269162, has been studied in healthy male volunteers to characterize how the body handles the drug.
RO7269162 is being developed by Roche Holding AG, which trades on the OTC market under the ticker RHHBY. Roche is the sponsor of the clinical program for this investigational small molecule.
RO7269162 is in Phase 1 clinical development. It is investigational and has not been approved by the FDA. One Phase 1 trial has been completed, and no active trials are currently listed for this asset.
RO7269162 has been evaluated in one completed Phase 1 trial, NCT06733298, titled A Study Investigating [14C]-Labeled RO7269162 in Healthy Male Participants. The trial enrolled 8 healthy male volunteers aged 35 years and older in the Netherlands. It was an uncontrolled study without randomization or double blinding.
[14C]-labeled RO7269162 is the carbon-14 radiolabeled form of RO7269162, used as a tracer in clinical research. The two names refer to the same investigational molecule. The labeled version was administered in the completed Phase 1 study NCT06733298 to track the drug's absorption, distribution, metabolism, and excretion in healthy volunteers.