Recent Updates
Recently added Catalysts

beta-lactam

Phase 2

Pneumonia, Bacterial | Small molecule | Infectious Disease |Roche Holding AG|Last Updated: Nov 2, 2016

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindACTIVE_CONTROLLED
Total Trials1
Total Enrollment302

FDA Designations

No designations recorded

Clinical trial landscape

beta-lactam · 1 trial · 1 indication

Phase 2 1
NCT00111644A Study to Assess Beta-Lactam in the Treatment of Hospitalized Patients With Bacterial PneumoniaPneumonia, Bacterial
COMPLETED302 Analytics
PHASE2COMPLETED
A Study to Assess Beta-Lactam in the Treatment of Hospitalized Patients With Bacterial Pneumonia
Pneumonia, BacterialUnlock trial analytics

Study Endpoints

Primary Endpoints

Clinical cure rate\n\n
End of study visit (7-10 days after end of treatment)

Secondary Endpoints

Adverse events, vital signs, laboratory parameters\n
Throughout study
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL -
2EXPERIMENTAL -
3ACTIVE_COMPARATOR -

Interventions

NameTypeDescription
CeftriaxoneDRUG1000mg iv daily
beta-lactamDRUG750mg iv q 23h for 3-14 days
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites49

Inclusion Criteria: * male or female patients at least 18 years of age; * hospitalization with community-acquired pneumonia or development of pneumonia within 48 hours of being hospitalized for another reason; * fever; * new or increased productive cough; * chest pain, shortness of breath, or rapid...

Countries:United StatesArgentinaBulgariaChileCroatiaHungaryLatviaLithuaniaPeruRomaniaSlovakia
Unlock Eligibility Criteria

Frequently asked questions about beta-lactam

What is beta-lactam used for?

Beta-lactam is an investigational small molecule being studied for the treatment of bacterial pneumonia in hospitalized patients. It is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

Who is developing beta-lactam?

Beta-lactam is being developed by Roche Holding AG, a biopharmaceutical company traded under the ticker RHHBY. The drug is in Phase 2 clinical development for bacterial pneumonia.

What phase is beta-lactam in?

Beta-lactam is in Phase 2 clinical development. It is an investigational drug and has not yet been approved for commercial use. A Phase 2 trial has been completed to assess its effects in patients with bacterial pneumonia.

What clinical trials is beta-lactam in?

Beta-lactam has one completed Phase 2 clinical trial, identified as NCT00111644. This randomized, double-blind, active-controlled study enrolled 302 hospitalized patients with bacterial pneumonia across multiple countries, including the United States, Argentina, Bulgaria, Chile, Croatia, Hungary, Latvia, Lithuania, Peru, Romania, and Slovakia.

Is beta-lactam the same as other antibiotics?

Beta-lactam is a small molecule antibiotic being studied for bacterial pneumonia. It is being developed by Roche Holding AG and is currently in Phase 2 clinical trials. No alternative names for this drug have been disclosed.