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Ro 205-2349

Phase 2

Diabetes | Small molecule | Metabolic |Roche Holding AG|Last Updated: Apr 28, 2023

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials2
Total Enrollment190

FDA Designations

No designations recorded

Clinical trial landscape

Ro 205-2349 · 2 trials · 1 indication

Phase 2 2
NCT00057304Study to Determine the Efficacy, Safety, Tolerability & Pharmacokinetics of RO 205-2349 in Patients With Type 2 Diabetes MellitusDiabetes
COMPLETED190 Analytics
NCT00057317Study of Ro 205-2349 in Patients With Type 2 Diabetes MellitusDiabetes
COMPLETED- Analytics
PHASE2COMPLETED
Study to Determine the Efficacy, Safety, Tolerability & Pharmacokinetics of RO 205-2349 in Patients With Type 2 Diabetes Mellitus
DiabetesUnlock trial analytics
PHASE2COMPLETED
Study of Ro 205-2349 in Patients With Type 2 Diabetes Mellitus
DiabetesUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
RO 205-2349 2 mg QDEXPERIMENTALRO 205-2349 2 mg was taken once daily (QD) for 16 weeks during the double-blind treatment period.
RO 205-2349 5 mg QDEXPERIMENTALRO 205-2349 5 mg was taken once daily (QD) for 16 weeks during the double-blind treatment period.

Interventions

NameTypeDescription
RO 205-2349DRUG -
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Eligibility Criteria

Age Range35 Years to 75 Years
SexALL
Healthy VolunteersNo
Study Sites46

Inclusion Criteria: * Age 35 to 75 * Type 2 diabetes for longer than 3 months * HbA1c (glycosylated hemoglobin A1c) greater than 7.0% at screening * FPG (fasting plasma glucose) greater than 126 mg/dL at screening * BMI (body mass index) less than 40 kg/square meter Exclusion Criteria: * Type I d...

Countries:United StatesBulgariaEstoniaMexicoPanamaPuerto RicoRomaniaSwitzerlandUnited KingdomCanadaLatviaLithuania
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Competitive Landscape -Diabetes Complications 6 trials (matched to "Diabetes")

Frequently asked questions about Ro 205-2349

What is Ro 205-2349 used for?

Ro 205-2349 is an investigational small molecule being developed for the treatment of diabetes, specifically type 2 diabetes mellitus. It is in Phase 2 clinical development and has been studied in patients with type 2 diabetes to evaluate its efficacy, safety, tolerability, and pharmacokinetics.

Who makes Ro 205-2349?

Ro 205-2349 is being developed by Roche Holding AG, a multinational healthcare company. Roche's stock is traded under the ticker symbol RHHBY on the OTC market.

What phase is Ro 205-2349 in?

Ro 205-2349 is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities. Two Phase 2 clinical trials have been completed, but the drug is not currently in active clinical trials.

What clinical trials is Ro 205-2349 in?

Ro 205-2349 has been studied in two completed Phase 2 clinical trials. The first trial, NCT00057304, enrolled 190 patients with type 2 diabetes mellitus across multiple countries. The second trial, NCT00057317, also studied patients with type 2 diabetes mellitus in several countries.

Is Ro 205-2349 the same as RO 205-2349?

Yes, Ro 205-2349 and RO 205-2349 refer to the same investigational drug. The name is sometimes written with different capitalization, but both refer to the same small molecule being developed by Roche for type 2 diabetes mellitus.