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RO6807952

Phase 1

Diabetes Mellitus Type 2 | Small molecule | Metabolic |Roche Holding AG|Last Updated: Nov 2, 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment45

FDA Designations

No designations recorded

Clinical trial landscape

RO6807952 · 1 trial · 1 indication

Phase 1 1
NCT01358929A Study of RO6807952 in Patients With Diabetes Mellitus Type 2Diabetes Mellitus Type 2
COMPLETED45 Analytics
PHASE1COMPLETED
A Study of RO6807952 in Patients With Diabetes Mellitus Type 2
Diabetes Mellitus Type 2Unlock trial analytics

Study Endpoints

Primary Endpoints

Safety: Incidence of adverse events
8 weeks

Secondary Endpoints

Blood concentrations of RO6807952
8 weeks
Effect of RO6807952 on Hemoglobin HbA1c level
8 weeks
Effect of RO6807952 on glucose level
8 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL -
2PLACEBO_COMPARATOR -

Interventions

NameTypeDescription
PlaceboDRUGPlacebo to RO6807952
RO6807952DRUGEscalating subcutaneous dose
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Eligibility Criteria

Age Range18 Years to 70 Years
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Adult patients, 18 to 70 years of age, inclusive * Diagnosis of type 2 diabetes \>/=3 months and \</=10 years prior to screening * Fasting plasma glucose \>/=110 mg/dL and \</=240 mg/dL * Patients on a stable dose of metformin for at least 2 months prior to screening * Hemoglo...

Countries:United States
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Frequently asked questions about RO6807952

What is RO6807952 used for?

RO6807952 is an investigational small molecule being studied for the treatment of Diabetes Mellitus Type 2. It is in Phase 1 clinical development and is not yet approved for any use.

Who makes RO6807952?

RO6807952 is being developed by Roche Holding AG, which trades under the ticker RHHBY. The company is conducting clinical trials to evaluate the drug's safety and efficacy in patients with Type 2 diabetes.

What phase is RO6807952 in?

RO6807952 is in Phase 1 clinical development. A Phase 1 study has been completed, but the drug remains investigational and has not been approved by regulatory authorities.

What clinical trials is RO6807952 in?

RO6807952 has one completed clinical trial, NCT01358929, which was a Phase 1 study in patients with Diabetes Mellitus Type 2. The trial enrolled 45 participants in the United States and was randomized, double-blind, and placebo-controlled.

Is RO6807952 FDA approved?

RO6807952 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development, and its safety and efficacy have not been established for the treatment of Type 2 diabetes.