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REGN20934

Phase 1

Overweight or Obesity | Small molecule | Metabolic |Regeneron Pharmaceuticals, Inc.|Last Updated: Jul 7, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment90

FDA Designations

No designations recorded

Clinical trial landscape

REGN20934 · 1 trial · 1 indication

Phase 1 1
NCT07594093Safety and Drug Concentrations of REGN20934 in Adults With Overweight or ObesityOverweight or Obesity
RECRUITING90 Analytics
PHASE1RECRUITING
Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity
Overweight or ObesityUnlock trial analytics

Study Endpoints

Primary Endpoints

Occurrence of Treatment Emergent Adverse Events (TEAEs)
Up to 16 weeks
Severity of TEAEs
Up to 16 weeks

Secondary Endpoints

REGN20934 concentration in serum
Up to 16 weeks
Occurrence of Anti-Drug Antibodies (ADAs) to REGN20934
Up to 16 weeks
Magnitude of ADAs to REGN20934
Up to 16 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelSEQUENTIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
REGN20934EXPERIMENTAL -
PlaceboPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
REGN20934DRUGAdministered per the protocol
PlaceboDRUGAdministered per the protocol
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersYes
Study Sites1

Key Inclusion Criteria: 1. Has a Body Mass Index (BMI) 25 to 35 kg/m\^2 2. Females must be of non-childbearing potential Key Exclusion Criteria: 1. A self-reported change of body weight \>5 kg within approximately 90 days of visit 2 2. History of type 1 or type 2 diabetes 3. History of clinically...

Countries:United States
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Recent Changes (Last 90 Days)

LOWJul 7, 2026NCT07594093Status: NOT_YET_RECRUITING → RECRUITING
LOWJul 7, 2026NCT07594093Status: NOT_YET_RECRUITING → RECRUITING

Frequently asked questions about REGN20934

What is REGN20934 and who is developing it?

REGN20934 is an investigational small molecule being developed by Regeneron Pharmaceuticals, Inc. for the treatment of overweight or obesity. It is currently in Phase 1 clinical development. The drug is being studied in a clinical trial in the United States.

What condition is REGN20934 being studied for?

REGN20934 is being studied for the treatment of overweight or obesity. The ongoing Phase 1 trial is enrolling adults who are overweight or obese. The trial is also open to healthy volunteers, as it is an early-stage study.

What is the current phase of development for REGN20934?

REGN20934 is currently in Phase 1 development. There is one active Phase 1 trial that is recruiting participants. No completed trials have been reported for this drug yet.

How is the Phase 1 trial for REGN20934 designed?

The Phase 1 trial, NCT07594093, is a randomized, double-blind, placebo-controlled study. It is designed to evaluate the safety and drug concentrations of REGN20934 in adults with overweight or obesity. The trial is recruiting 90 participants in the United States.

Who is eligible to participate in the REGN20934 trial?

The trial is open to adults aged 18 years and older, of all sexes. It includes participants who are overweight or obese, and also accepts healthy volunteers. The study is being conducted in the United States.

Is REGN20934 a biologic or a small molecule?

REGN20934 is a small molecule, not a biologic. It is being developed as a potential treatment for overweight or obesity. The drug is currently in Phase 1 testing to assess its safety and pharmacokinetics.