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REGN1908

Phase 3

Allergic Conjunctivitis | Small molecule | Ophthalmology |Regeneron Pharmaceuticals, Inc.|Last Updated: May 8, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment64

FDA Designations

No designations recorded

Clinical trial landscape

REGN1908 · 1 trial · 1 indication

Phase 3 1
NCT06602726A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat AllergyAllergic Conjunctivitis
COMPLETED64 Analytics
PHASE3COMPLETED
A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy
Allergic ConjunctivitisUnlock trial analytics

Study Endpoints

Primary Endpoints

Ocular itch score
At day 8 post-Conjunctival Allergen Challenge (CAC)

Assessed using the Ora Calibra® Conjunctival Allergen Challenge Ocular Itching Scale, a 0-4 point scale where 0= none and 4= incapacitating itch, 0.5 unit increments

Secondary Endpoints

Conjunctival redness score
At day 8 post-CAC
Percent change in cat titrated Skin prick test (tSPT)
Baseline and day 8
Tearing score
At day 8 post-CAC
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
REGN1908-1909EXPERIMENTAL -
PlaceboPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
REGN1908DRUGAdministered per the protocol
REGN1909DRUGAdministered per the protocol
PlaceboDRUGAdministered per the protocol
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites4

Key Inclusion Criteria: 1. Documented or participant-reported history of moderate to severe cat allergy for at least 2 years with bothersome ocular symptoms being near cat(s) 2. Positive SPT with cat allergen extract (mean wheal diameter at least 5 mm greater than the negative control) at screening...

Countries:United StatesCanada
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Recent Changes (Last 90 Days)

MEDIUMJun 8, 2026NCT06602726TRIAL_REMOVED: changed
MEDIUMJun 8, 2026NCT06602726TRIAL_REMOVED: changed
MEDIUMJun 8, 2026NCT06602726TRIAL_REMOVED: changed
MEDIUMJun 8, 2026NCT06602726TRIAL_REMOVED: changed
MEDIUMJun 8, 2026NCT06602726TRIAL_REMOVED: changed

Frequently asked questions about REGN1908

What is REGN1908 used for?

REGN1908 is an investigational small molecule being developed by Regeneron Pharmaceuticals for the treatment of allergic conjunctivitis, specifically in adult participants with cat allergy. It is currently in Phase 3 clinical development, though the single completed trial did not lead to an approved indication.

Who makes REGN1908?

REGN1908 is being developed by Regeneron Pharmaceuticals, Inc., a biopharmaceutical company traded on the Nasdaq under the ticker symbol REGN. The company is conducting clinical trials to evaluate the drug's efficacy in reducing ocular allergy signs and symptoms.

What phase is REGN1908 in?

REGN1908 is in Phase 3 clinical development. The drug is investigational and has not been approved by regulatory authorities. A Phase 3 trial has been completed, but the drug remains in clinical development and is not yet available for commercial use.

What clinical trials is REGN1908 in?

REGN1908 has been studied in one clinical trial, identified as NCT06602726. This Phase 3, randomized, double-blind, placebo-controlled study enrolled 64 adult participants with cat allergy and allergic conjunctivitis. The trial was conducted in the United States and Canada and has been completed.

Is REGN1908 the same as REGN1908-1909?

REGN1908 is part of a combination product referred to as REGN1908-1909 in the clinical trial NCT06602726. The study evaluates the combination of REGN1908 and REGN1909, though REGN1908 is listed as the primary drug name in the development program.