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Valacyclovir

Phase 1

Healthy | Small molecule | Other |Dr. Reddy's Laboratories Ltd|Last Updated: Jun 14, 2010

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDDMC
Total Trials2
Total Enrollment75

FDA Designations

No designations recorded

Clinical trial landscape

Valacyclovir · 2 trials · 1 indication

Phase 1 2
NCT01136525Bioavailability Study of Valacyclovir HCl Tablets, 1000 mg of Dr. Reddy's Under Fasting ConditionsHealthy
COMPLETED41 Analytics
NCT01136538Bioavailability Study of Valacycovir HCl Tablets, 1000 mg of Dr. Reddy's Under Fed ConditionHealthy
COMPLETED34 Analytics
PHASE1COMPLETED
Bioavailability Study of Valacyclovir HCl Tablets, 1000 mg of Dr. Reddy's Under Fasting Conditions
HealthyUnlock trial analytics
PHASE1COMPLETED
Bioavailability Study of Valacycovir HCl Tablets, 1000 mg of Dr. Reddy's Under Fed Condition
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence based on Cmax and AUC parameters
4 months
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Valacyclovir HydrochlorideEXPERIMENTALValacyclovir Hydrochloride Tablets, 1000 mg of Dr. Reddy's Laboratories Limited
Valtrex (R)ACTIVE_COMPARATORValtrex (R) (Valacyclovir Hydrochloride) CAPLETS 1 gram of GlaxoSmithkline

Interventions

NameTypeDescription
Valacyclovir HydrochlorideDRUGValacyclovir Hydrochloride Tablets, 1000 mg of Dr. Reddy's Laboratories Limited
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Eligibility Criteria

Age Range18 Years to 45 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: The subjects were selected for study participation, based on the following criteria: 1. Human subjects aged between 18 and 45 years (including both). 2. Subjects' weight within the normal range according to normal values for the Body Mass Index (18.5 to 24.9 kg/m2) with minimum...

Countries:India
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Frequently asked questions about Valacyclovir

What is Valacyclovir used for?

Valacyclovir is an antiviral small molecule being studied in healthy volunteers. It is currently in Phase 1 clinical development by Dr. Reddy's Laboratories Ltd. The ongoing studies are bioavailability trials, which assess how the drug is absorbed and processed in the body under fasting and fed conditions.

Who makes Valacyclovir?

Valacyclovir is being developed by Dr. Reddy's Laboratories Ltd, a pharmaceutical company listed on the stock exchange under the ticker RDY. The company is conducting Phase 1 clinical trials for this drug in healthy volunteers.

What phase is Valacyclovir in?

Valacyclovir is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The current Phase 1 trials are bioavailability studies conducted in healthy volunteers to evaluate how the drug behaves in the body.

What clinical trials is Valacyclovir in?

Valacyclovir has two completed Phase 1 clinical trials. The first, NCT01136525, is a bioavailability study of Valacyclovir HCl Tablets, 1000 mg under fasting conditions with 41 participants. The second, NCT01136538, is a bioavailability study under fed conditions with 34 participants. Both trials were conducted in India.

Is Valacyclovir the same as Valacyclovir HCl?

Valacyclovir HCl is the hydrochloride salt form of Valacyclovir. The clinical trials for Valacyclovir conducted by Dr. Reddy's Laboratories use Valacyclovir HCl Tablets, 1000 mg, indicating that the drug is administered in this salt form.