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Prilosec

Phase 1

Healthy | Small molecule | Other |Dr. Reddy's Laboratories Ltd|Last Updated: Jul 27, 2010

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment44
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01170169Omeprazole Delayed Release (DR) Capsules Bioequivalence Study of Dr. Reddys Under Fasting ConditionsPHASE1 COMPLETED 44Jan 1, 2006Mar 1, 2006Jul 27, 2010 -
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Study Endpoints
Primary Endpoints
Bioequivalence based on Cmax and AUC parameters
5 months
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
OmeprazoleEXPERIMENTALOmeprazole Delayed Release Capsules of Dr. Reddy's laboratories limited
PrilosecACTIVE_COMPARATORPrilosec® 40 mg of Merck \& Co.Inc.
Interventions
NameTypeDescription
OmeprazoleDRUGOmeprazole Delayed Release Capsules 40 mg
PrilosecDRUGPrilosec® 40 mg of Merck \& Co.Inc.
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Eligibility Criteria
Age Range18 Years — 45 Years
SexALL
Healthy VolunteersYes

Inclusion Criteria: * Subjects who provided written informed consent. * Subjects who were healthy within 18-45 years of age, weighing at least 50 kg. * Body mass index of ≥ 18 kglm2 and ≤ 25 kg/m2, with body weight not less than 50 kg. * Subjects with normal health as determined by medical history ...

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