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Lamictal

Phase 1

Healthy | Small molecule | Other |Dr. Reddy's Laboratories Ltd|Last Updated: Jan 20, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials2
Total Enrollment40

FDA Designations

No designations recorded

Clinical trial landscape

Lamictal · 2 trials · 1 indication

Phase 1 2
NCT01513720Bioequivalence Study for Lamotrigine Tablets 200 mg Under Fasting ConditionHealthy
COMPLETED20 Analytics
NCT01513681Bioequivalence Study for Lamotrigine Tablets 200 mg Under Fed ConditionHealthy
COMPLETED20 Analytics
PHASE1COMPLETED
Bioequivalence Study for Lamotrigine Tablets 200 mg Under Fasting Condition
HealthyUnlock trial analytics
PHASE1COMPLETED
Bioequivalence Study for Lamotrigine Tablets 200 mg Under Fed Condition
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Area under curve (AUC)
Pre-dose 0.5,1,1.5,2,2.5,3,3.5,4,5,6,8,12,24,36,48,72,96,120 hours
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Lamotrigine Tablets 200 mgEXPERIMENTALLamotrigine Tablets 200 mg of Dr. Reddy's Laboratories Limited
Lamictal® 200 mg TabletsACTIVE_COMPARATORLamictal® 200 mg Tablets of GlaxoSmithKline Inc

Interventions

NameTypeDescription
LamotrigineDRUGLamotrigine Tablets 200 mg
Lamictal®DRUGLamictal® 200 mg Tablets
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Eligibility Criteria

Age Range20 Years to 44 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Healthy males and females at least 18 years of age inclusive 2. Informed of the nature of the study and given written informed consent 3. Have a body weight within 15% of the appropriate range as defined in the 1983 Metropolitan Life Company tables and weighing at least 100 l...

Countries:United States
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Frequently asked questions about Lamictal

What is Lamictal used for?

Lamictal is being studied in healthy volunteers in Phase 1 bioequivalence trials. It is a small molecule drug being developed by Dr. Reddy's Laboratories Ltd. The trials are designed to compare the absorption of Lamotrigine Tablets 200 mg under fed and fasting conditions.

Who makes Lamictal?

Lamictal is being developed by Dr. Reddy's Laboratories Ltd, which trades under the ticker RDY. The company is conducting Phase 1 bioequivalence studies for Lamotrigine Tablets 200 mg in healthy volunteers in the United States.

What phase is Lamictal in?

Lamictal is in Phase 1 clinical development. Two Phase 1 bioequivalence studies have been completed, each enrolling 20 healthy volunteers. The drug is investigational and not yet approved for any indication.

What clinical trials is Lamictal in?

Lamictal has two completed Phase 1 trials: NCT01513681, a bioequivalence study under fed conditions, and NCT01513720, a bioequivalence study under fasting conditions. Both enrolled 20 healthy volunteers in the United States and were active-controlled, randomized studies.

Is Lamictal the same as Lamotrigine?

Yes, Lamictal is the brand name for lamotrigine. The clinical trials listed for Lamictal are specifically for Lamotrigine Tablets 200 mg, testing bioequivalence under fed and fasting conditions in healthy volunteers.