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Eszopiclone

Phase 1

Healthy | Small molecule | Other |Dr. Reddy's Laboratories Ltd|Last Updated: Dec 23, 2014

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedACTIVE_CONTROLLEDDMCBiomarker
Total Trials2
Total Enrollment92
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT02322658Bioequivalence Study of Eszopiclone Tablets, 3 mg Under Fed ConditionsPHASE1 COMPLETED 46Sep 1, 2008Oct 1, 2008Dec 23, 20141 India
NCT02322645Bioequivalence Study of Eszopiclone Tablets, 3 mg Under Fasting ConditionsPHASE1 COMPLETED 46Aug 1, 2008Oct 1, 2008Dec 23, 20141 India
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Study Endpoints
Primary Endpoints
Area under curve
0.25, 0.5, 0.75, 1.0, 1.25, 1.5, 1.75, 2.0, 2.5, 3.0, 3.5, 4.0, 5.0, 6.0, 8.0, 10.0, 12.0, 24.0, 36.0 and 48.0 hours post dose.
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Eszopiclone TabletsEXPERIMENTALEszopiclone Tablets 3 mg of Dr. Reddy's Laboratories Limited
LunestaACTIVE_COMPARATORLunesta Tablets 3 mg of Sepracor Inc.
Interventions
NameTypeDescription
Eszopiclone Tablets 3 mgDRUG -
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Eligibility Criteria
Age Range18 Years — 45 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. The subjects should be healthy human between 18 and 45 years. 2. The subjects should be screened within 21 days prior to the administration of first dose of the study drug. 3. The subjects should have a BMI between 18.5 and 24.9 weight in kg/ height2 in meter. 4. The subjects...

Countries:India
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