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LYT-200

Phase 2

Metastatic Cancer | Small molecule | Oncology |PureTech Health plc|Last Updated: Feb 11, 2025

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment44
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04666688LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid TumorsPHASE1/PHASE2 COMPLETED 44Dec 1, 2020Dec 1, 2024Feb 11, 2025 -
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Study Design & Arms
Interventions
NameTypeDescription
LYT-200DRUGmonoclonal antibody (mAb), targeting galectin-9 protein
TislelizumabDRUGanti-PD-1 monoclonal antibody
Gemcitabine/nab-paclitaxelDRUGchemotherapy
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