Recent Updates
Recently added Catalysts

pseudoephedrine

Phase 3

Nasal Congestion Associated With the Common Cold | Small molecule | Infectious Disease |Perrigo Company plc|Last Updated: Apr 22, 2016

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment565

FDA Designations

No designations recorded

Clinical trial landscape

pseudoephedrine · 1 trial · 1 indication

Phase 3 1
NCT01744106A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common ColdNasal Congestion Associated With the Common Cold
COMPLETED565 Analytics
PHASE3COMPLETED
A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold
Nasal Congestion Associated With the Common ColdUnlock trial analytics

Study Endpoints

Primary Endpoints

Nasal Congestion Severity (NCSi) (instantaneous) scores
1 Day

Weighted sum of change from baseline in Nasal Congestion Severity (NCSi) (instantaneous) scores over the first eight hours of treatment on Day 1

Secondary Endpoints

change from baseline in NCSi scores from 0 to 4 hours
Day 1
change from baseline in NCSi scores from 6, 7, and 8 hours
Day 1
Nasal Congestion Relief (NCR) reflective scores at 4 hours and 8 hours
Day 1
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
pseudoephedrine hydrochloride 30 mg tabletsEXPERIMENTALTest product
placebo tabletsPLACEBO_COMPARATORPlacebo

Interventions

NameTypeDescription
pseudoephedrine hydrochloride 30 mg tabletsDRUG -
Placebo tabletsDRUG -
Unlock Study Design Details

Eligibility Criteria

Age Range6 Years to 11 Years
SexALL
Healthy VolunteersNo
Study Sites11

Inclusion Criteria: 1. Male or female subjects, ages 6 through 11 years, are experiencing the common cold, but are otherwise healthy. 2. Subjects have an onset of cold symptoms within the past 2.5 days before screening and are experiencing self-reported nasal congestion of at least stuffy severity ...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about pseudoephedrine

What is pseudoephedrine used for?

Pseudoephedrine is used for the temporary relief of nasal congestion associated with the common cold. It is being studied in children aged 6 years and older for this indication. The drug is a small molecule and is currently in Phase 3 clinical development.

Who makes pseudoephedrine?

Pseudoephedrine is being developed by Perrigo Company plc, which trades under the ticker PRGO. The company is conducting clinical trials for the drug in the United States for the treatment of nasal congestion associated with the common cold.

What phase is pseudoephedrine in?

Pseudoephedrine is in Phase 3 clinical development. It is an investigational drug for the temporary relief of nasal congestion associated with the common cold in children. The drug has completed one Phase 3 trial and is not yet approved.

What clinical trials is pseudoephedrine in?

Pseudoephedrine has one completed Phase 3 clinical trial, identified as NCT01744106. This multicenter study evaluated the drug for the temporary relief of nasal congestion in children with the common cold. The trial enrolled 565 participants in the United States and was randomized, double-blind, and placebo-controlled.

Is pseudoephedrine FDA approved?

Pseudoephedrine is not FDA approved for the indication of nasal congestion associated with the common cold in children. It is currently in Phase 3 clinical development, meaning it is still being studied and has not yet received regulatory approval.

How does pseudoephedrine work?

Pseudoephedrine is a small molecule used to relieve nasal congestion. It works by reducing swelling in the nasal passages, which helps to open up the airways and ease breathing. This mechanism is being evaluated in clinical trials for children with the common cold.