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PRX-102

Phase 3

Fabry Disease | Small molecule | Metabolic |Protalix BioTherapeutics, Inc. (DE)|Last Updated: Sep 12, 2023

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials4
Total Enrollment133
FDA Designations
No designations recorded
Clinical Trials (4)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT03018730Safety and Efficacy of PRX-102 in Patients With Fabry Disease Currently Treated With REPLAGAL® (Agalsidase Alfa)PHASE3 COMPLETED 22May 1, 2017Jan 1, 2020Sep 12, 2023 -
NCT02795676Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal FunctionPHASE3 COMPLETED 78Jun 1, 2016Jul 1, 2022Sep 12, 2023 -
NCT01981720Extension Study of PRX-102 for up to 60 MonthsPHASE1/PHASE2 COMPLETED 15Jan 1, 2014Nov 1, 2021Sep 12, 2023 -
NCT01678898Dose-ranging Study of PRX-102 in Adult Fabry Disease PatientsPHASE1/PHASE2 COMPLETED 18Oct 1, 2012Mar 1, 2016Sep 12, 2023 -
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Study Design & Arms
Interventions
NameTypeDescription
PRX-102 (pegunigalsidase alfa)BIOLOGICALPRX-102 1 mg/kg every 2 weeks
agalsidase betaBIOLOGICALagalsidase beta 1 mg/kg every 2 weeks
PRX-102DRUG -
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