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BX002-A

Phase 1

Healthy Volunteers | Monoclonal antibody | Other |BiomX Inc.|Last Updated: Jan 25, 2022

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedPLACEBO_CONTROLLED
Total Trials1
Total Enrollment18
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04737876A Study to Evaluate the Safety, Tolerability, and Fecal Pharmacokinetics of BX002-A in Healthy AdultsPHASE1 COMPLETED 18Oct 28, 2020Dec 21, 2020Jan 25, 20221 United States
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Study Endpoints
Primary Endpoints
Safety and Tolerability: adverse events
Through study completion Day 31 (+ 2 days)

Evaluated by reviewing adverse events

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Study Design & Arms
AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeOTHER
Treatment Arms
ArmTypeDescription
BX002-AEXPERIMENTALBX002-A: 1 mL liquid for multiple dose oral administration
PlaceboPLACEBO_COMPARATORPlacebo: 1 mL liquid for multiple dose oral administration
Interventions
NameTypeDescription
BX002-ABIOLOGICALbacteriophage cocktail
PlaceboOTHERPlacebo
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Eligibility Criteria
Age Range18 Years — 65 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Healthy adults 18-65 years old 2. Able to understand study procedures and sign informed consent Exclusion Criteria: 1. Evidence or history of clinically significant underlying conditions 2. Women who are pregnant or nursing, or plan to become pregnant during study, or women...

Countries:United States
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