Financials
Cash Data
- Cash FlowProfitable
- SEC Filing
Key Stats
Upcoming Catalysts
FDA decisions, readouts and PDUFA dates · scored by probability of approval
PFE Catalyst Timeline
Dated clinical, regulatory and corporate events for Pfizer, Inc.
Catalyst Timeline
Dated clinical, regulatory & corporate events for Pfizer, Inc.
Upcoming catalysts 2
Event history 50
Past FDA Catalysts and PDUFA Decisions
How PFE actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2026-10-26 | TALZENNA plus XTANDI (talazoparib + enzalutamide) | PDUFA Date Approved | PDUFA |
Drug Pipeline Intelligence
| Product | Revenue | Prior period | Change |
|---|---|---|---|
| Eliquis | |||
| Vyndaqel | |||
| Prevnar family | |||
| Ibrance | |||
| Comirnaty | |||
| Padcev | |||
| Xtandi | |||
| Paxlovid, EUA-Labeled | |||
| Nurtec ODT/Vydura | |||
| Lorbrena | |||
| Abrysvo | |||
| Xeljanz |
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ibuzatrelvir Small moleculeNCT06679140 | COVID-19 SARS-CoV-2 Infection | Phase 3 | RECRUITING | 2,330 | Feb 12, 2028 | ||||||
| ibuzatrelvir Small moleculeNCT07013474 | COVID-19 Infection | Phase 3 | RECRUITING | 300 | Feb 5, 2028 | ||||||
| tilrekimig and rHuPH20 Small moleculeNCT07765888 | Atopic Dermatitis | Phase 3 | RECRUITING | 1,750 | Jun 2, 2028 | ||||||
| tilrekimig and rHuPH20 Small moleculeNCT07772921 | Asthma | Phase 3 | RECRUITING | 2,200 | Aug 24, 2029 | ||||||
| tilrekimig and rHuPH20 Small moleculeNCT07839884 | Moderate to Severe Chronic Obstructive Pulmonary Disease | Phase 3 | NOT YET_RECRUITING | 1,360 | May 12, 2034 | ||||||
| PF-07275315 Small moleculeNCT05995964 | Atopic Dermatitis | Phase 2 | ACTIVE NOT_RECRUITING | 507 | Apr 1, 2027 | ||||||
| PF-07275315 Small moleculeNCT07363694 | Moderate to Severe Chronic Obstructive Pulmonary Disease | Phase 2 | RECRUITING | 1,156 | Jan 16, 2031 | ||||||
| PF-07275315 Small moleculeNCT06977581 | Asthma | Phase 2 | RECRUITING | 252 | May 31, 2027 | ||||||
| Fidanacogene elaparvovec Gene therapyNCT03861273 | Hemophilia B | Phase 3 | ACTIVE NOT_RECRUITING | 51 | Feb 25, 2028 | ||||||
| sigvotatug vedotin ADCNCT06758401 | Non-Small Cell Lung Cancer | Phase 3 | RECRUITING | 714 | Mar 1, 2029 | ||||||
| sigvotatug vedotin ADCNCT06012435 | Carcinoma, Non-Small Cell Lung | Phase 3 | ACTIVE NOT_RECRUITING | 1,774 | May 17, 2028 | ||||||
| PF-08634404 Monoclonal antibodyNCT07222566 | Advanced Non-Small Cell Lung Cancer | Phase 3 | RECRUITING | 1,410 | Aug 26, 2032 | ||||||
| PF-08634404 Monoclonal antibodyNCT07578649 | Endometrial Neoplasms | Phase 3 | NOT YET_RECRUITING | 600 | Jan 30, 2031 | ||||||
| PF-08634404 Small moleculeNCT07222800 | Intestinal Neoplasms | Phase 3 | RECRUITING | 800 | Aug 17, 2031 | ||||||
| PF-08634404 Monoclonal antibodyNCT07392892 | Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma | Phase 2 | RECRUITING | 840 | Jul 21, 2032 | ||||||
| PF-08634404 Small moleculeNCT07226999 | Small Cell Lung Cancer | Phase 2 | RECRUITING | 590 | Mar 11, 2034 | ||||||
| PF-08634404 Monoclonal antibodyNCT07489066 | Carcinoma | Phase 2 | RECRUITING | 120 | Jul 30, 2031 | ||||||
| PF-08634404 Monoclonal antibodyNCT07227298 | Advanced/Metastatic Non-Small Cell Lung Cancer | Phase 1 | RECRUITING | 162 | Aug 23, 2033 | ||||||
| PF-08634404 Monoclonal antibodyNCT07227012 | Carcinoma, Hepatocellular | Phase 1 | RECRUITING | 138 | Oct 17, 2028 | ||||||
| PF-08634404 Monoclonal antibodyNCT07421700 | Urothelial Cancer | Phase 1 | RECRUITING | 132 | Sep 25, 2028 | ||||||
| PF-08634404 Small moleculeNCT07227415 | Carcinoma, Renal Cell | Phase 1 | RECRUITING | 224 | Nov 1, 2028 | ||||||
| PF-08046054 Small moleculeNCT07144280 | Non-small Cell Carcinoma | Phase 3 | RECRUITING | 680 | Mar 10, 2032 | ||||||
| PF-08046054 Small moleculeNCT05208762 | Carcinoma, Non-Small-Cell Lung | Phase 1 | RECRUITING | 714 | Jan 4, 2029 | ||||||
| PF-07220060 Small moleculeNCT07890597 | Early Breast Cancer | Phase 3 | NOT YET_RECRUITING | 3,800 | Aug 20, 2042 | ||||||
| PF-07220060 Small moleculeNCT05262400 | Breast Cancer | Phase 3 | ACTIVE NOT_RECRUITING | 1,391 | Feb 26, 2027 |
Clinical Trial Results
Readouts, endpoints and source filings for every PFE program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| PF-07872412 | pneumococcal disease | Phase 2 | 2026-10-24 | strong immune responses across all 25 serotypes in infantsRead More | Pfizer's 25-Valent Pediatric Pneumococcal Conjugate Vaccine Candidate Shows Robust Phase 2 Data at IDWeek 2026Read More |
Inside Trades
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| BOURLA ALBERTDirector, Officer (Chairman & CEO) | Buy | 38,000 429,173 held | $26.34 | 08/12/2026 |
Hedge Fund 13F Activity
Hedge Funds invested in PFE
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| PROSIGHT MANAGEMENT, LP | 0.6 % (-64.7 %) | 3.26 M | 135.37 K | -37.04% ( -79.63 K) |
PFE Institutional Ownership Trends
PFE Short Interest
Shares sold short, counted twice a month.
Options Data
Option Volume
Option Chain Statistics
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-10-30 | ||||||||||||
Real-Time Option Chain
| Calls | Strike | Puts | ||||
|---|---|---|---|---|---|---|
| Last | Vol | OI | Last | Vol | OI | |
| No data available | ||||||
Calls vs Puts by Expiry
Competitive positioning
How PFE ranks across every disease it competes in
PFE News
Pfizer’s TALZENNA Plus XTANDI FDA-Approved for an Earlier Metastatic Prostate Cancer Treatment Setting
Pfizer announced FDA approval for TALZENNA in combination with XTANDI for treating men with HRR gene-mutated metastatic prostate cancer. This approval is based on Phase 3 TALAPRO-3 data, demonstrating a 52% reduction in the risk of radiographic progression or death. The combination therapy is now available earlier in the treatment course, potentially benefiting more patients.
Read more →Pfizer's 25-Valent Pediatric Pneumococcal Conjugate Vaccine Candidate Shows Robust Phase 2 Data at IDWeek 2026
Pfizer's investigational 25-valent pneumococcal conjugate vaccine, PF-07872412, demonstrated strong immune responses in infants during a Phase 2 study. The vaccine showed safety comparable to PREVNAR 20 and elicited robust responses against all 25 serotypes, including five new ones. These results support ongoing Phase 3 trials aimed at enhancing protection against invasive pneumococcal disease in children.
Read more →Pfizer Showcases Clinical Advancements Across Infectious Diseases at IDWeek 2026
Pfizer will present data from over 50 research abstracts at IDWeek 2026, focusing on advancements in infectious disease vaccines, including pneumococcal and Lyme disease vaccines. Key highlights include promising results from Phase 2 and Phase 3 studies on next-generation vaccines. The company emphasizes its commitment to addressing urgent public health challenges through innovative vaccine development.
Read more →Enodia Therapeutics Announces Research Collaboration and License Agreement with Pfizer to Develop Sec61-Targeting Small Molecules
Enodia Therapeutics has entered a research collaboration and license agreement with Pfizer to develop Sec61 inhibitors. This partnership aims to leverage Enodia's proprietary platform for discovering small-molecule therapeutics that inhibit disease-driving proteins while preserving essential functions. Enodia will handle discovery activities, with Pfizer taking over clinical and commercial responsibilities post-collaboration. The agreement could be worth over $500 million.
Read more →Pfizer’s TUKYSA Regimen Receives FDA Approval as Front-Line Maintenance Treatment for HER2+ Metastatic Breast Cancer
Pfizer has received FDA approval for TUKYSA (tucatinib) in combination with trastuzumab and pertuzumab. This approval allows the drug to be used as a maintenance treatment for adults with unresectable locally advanced or metastatic HER2+ breast cancer following induction therapy. This marks a significant advancement in treatment options for patients at an earlier stage of metastatic disease.
Read more →Pfizer Declares Fourth-Quarter 2026 Dividend
Pfizer Inc. has declared a $0.43 dividend for the fourth quarter of 2026, payable on December 7, 2026. This decision reflects the company's ongoing commitment to its capital allocation strategy, aiming to maintain and grow dividends over time. The upcoming dividend will be the 352nd consecutive payment to shareholders.
Read more →Pfizer’s LITFULO Significantly Improved Facial and Total Body Repigmentation in Patients with Nonsegmental Vitiligo
Pfizer Inc. presented positive results from two Phase 3 trials for LITFULO (ritlecitinib), demonstrating significant improvements in facial and total body repigmentation in patients with nonsegmental vitiligo. The trials, TRANQUILLO 2 and TRANQUILLO, showed that both 100 mg and 50 mg dosages outperformed placebo. Patient-reported outcomes further supported these findings, indicating reduced disease severity.
Read more →Pfizer's Tilrekimig Shows Significant Skin Clearance in Phase 2 Atopic Dermatitis Study
Pfizer presented positive results from a Phase 2 study of tilrekimig for atopic dermatitis. The study achieved its primary endpoint, showing a significant increase in skin clearance among participants. This was measured by the Eczema Area and Severity Index at Week 16, indicating promising efficacy for the treatment.
Read more →Professor Bill Sessa, Former Chief Scientific Officer of Internal Medicine at Pfizer, Appointed Chair of Isomab's Scientific Advisory Board
Isomab Ltd has appointed Professor Bill Sessa as Chair of its Scientific Advisory Board. He will lead a team of distinguished vascular biologists as the company advances its first-in-class anti-VEGF-A165b antibody, ISM-001, towards clinical trials for chronic angina. This strategic move aims to enhance the development of novel therapies for patients with cardiovascular diseases.
Read more →Pfizer Advances Today’s Cancer Care and Tomorrow's Potential Breakthroughs at ESMO
Pfizer Inc. will present 45 research abstracts at the upcoming ESMO Congress in Madrid. The presentations will include 11 oral presentations highlighting advancements in cancer treatments, particularly in breast, genitourinary, and lung cancers. This event underscores Pfizer's commitment to enhancing cancer care and exploring future breakthroughs.
Read more →Pfizer Invites Public to View and Listen to Webcast of November 3 Conference Call with Analysts
Pfizer Inc. has announced a conference call scheduled for November 3, 2026, at 10:00 a.m. EST. The call aims to update investors on the company's third quarter performance. Participants can access the webcast and the performance report through Pfizer's investor website.
Read more →Health Canada Authorizes Pfizer and BioNTech's Omicron XFG-Adapted COVID-19 Vaccine
Health Canada has authorized Pfizer and BioNTech's updated COMIRNATY vaccine for the 2026-2027 season, specifically targeting the Omicron XFG variant. This approval is based on extensive clinical and real-world data demonstrating the vaccine's safety and effectiveness. The vaccine will be available through various channels, ensuring equitable access across Canada.
Read more →Pfizer Invites Public to Listen to Webcast of Pfizer Discussion at Healthcare Conference
Pfizer Inc. is inviting the public and investors to listen to a webcast featuring Alexandre de Germay, the Chief International Commercial Officer, at the J.P. Morgan U.S. All Stars 2026 Conference. The event is scheduled for September 22, 2026, at 11:50 a.m. BST. Details for accessing the webcast can be found on Pfizer's investor website.
Read more →Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vaccine
Pfizer and BioNTech have received FDA approval for their 2026-2027 COVID-19 vaccine, which targets the XFG variant. The vaccine is intended for adults aged 65 and older, as well as younger individuals with underlying health conditions. Shipping of the vaccine will commence immediately to ensure timely access. The approval is based on comprehensive data demonstrating the vaccine's effectiveness against various SARS-CoV-2 variants.
Read more →Legal Bay Pre-Settlement Funding Reports Pfizer Agrees to Settle Depo-Provera Birth Control Litigation
Pfizer has agreed to a settlement program to resolve a substantial number of lawsuits alleging that Depo-Provera caused intracranial meningiomas. Legal Bay estimates that around 5,000 claims could settle for over $1.2 billion. The financial terms remain confidential, and actual compensation will depend on various factors. The settlement is seen as a significant development for affected claimants.
Read more →Pfizer and Valneva’s Lyme Disease Vaccine Candidate Marketing Authorization Application Validated by European Medicines Agency
Pfizer and Valneva announced that the European Medicines Agency has validated their Marketing Authorization Application for PF-07307405, a Lyme disease vaccine candidate. This application is based on positive results from the Phase 3 VALOR trial, which demonstrated over 70% efficacy. The vaccine was well tolerated, with no safety issues reported, marking a significant step in addressing Lyme disease in Europe.
Read more →Pfizer Reports Second-Quarter Results And Raises Midpoint of 2026 Revenue Guidance
Pfizer Inc. reported its second-quarter financial results for 2026, showcasing a strong performance. The company raised its full-year revenue guidance by $500 million at the midpoint while reaffirming its adjusted diluted EPS guidance. CEO Dr. Albert Bourla highlighted the company's commitment to delivering on financial expectations.
Read more →Pfizer Announces Positive Topline Phase 3 Results for LITFULO in Patients with Nonsegmental Vitiligo
Pfizer has reported positive topline results from two Phase 3 trials of LITFULO for treating nonsegmental vitiligo. The trials assessed the drug's efficacy and safety in patients with varying disease severity. Both studies showed significant results for the 50 and 100 milligram doses, indicating a promising treatment option.
Read more →