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procarbazine

Phase 3

Brain and Central Nervous System Tumors | Small molecule | Oncology |Pfizer, Inc.|Trials Updated: Sep 11, 2012

procarbazine development status

Highest phase Phase 3
Registered trials 2 across 2 sponsors since Aug 2021

procarbazine target and mechanism

ModalitySmall molecule

Also known as procarbazine hydrochloride

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

procarbazine clinical trials

procarbazine · 1 trial · 1 indication

Phase 3 1
NCT00003293SU-101 Compared With Procarbazine in Treating Patients With Glioblastoma MultiformeBrain and Central Nervous System Tumors
COMPLETED- Analytics
PHASE3COMPLETED
SU-101 Compared With Procarbazine in Treating Patients With Glioblastoma Multiforme
Brain and Central Nervous System TumorsUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
PurposeTREATMENT

Interventions

NameTypeDescription
leflunomideDRUG -
procarbazine hydrochlorideDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites35

DISEASE CHARACTERISTICS: Histologically proven refractory or recurrent supratentorial glioblastoma multiforme Bidimensionally measurable, enhancing residual disease by T1-weighted gadolinium-enhanced MRI required within 15 days prior to treatment Stable dose of corticosteroids required for at least ...

Countries:United StatesCanada
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Frequently asked questions about procarbazine

What is procarbazine used for?

Procarbazine is used in the treatment of brain and central nervous system tumors, including glioblastoma multiforme. It is an oncology small molecule that has been studied in a Phase 3 trial comparing it with another agent in patients with glioblastoma multiforme. It is also known as procarbazine hydrochloride.

Who makes procarbazine?

Procarbazine is developed by Pfizer, Inc., which trades on the New York Stock Exchange under the ticker symbol PFE. Pfizer is the company associated with the clinical development of procarbazine for brain and central nervous system tumors.

What phase is procarbazine in?

Procarbazine has been evaluated in a Phase 3 clinical trial. The trial, NCT00003293, is completed. There are no active trials of procarbazine listed. The drug is investigational in this development program and is not described as approved.

What clinical trials is procarbazine in?

Procarbazine was studied in one Phase 3 clinical trial, NCT00003293, titled SU-101 Compared With Procarbazine in Treating Patients With Glioblastoma Multiforme. The trial was completed, was randomized, and enrolled patients in the United States and Canada. It included adults 18 years and older of all sexes.

Is procarbazine the same as procarbazine hydrochloride?

Yes, procarbazine is also known as procarbazine hydrochloride. The two names refer to the same drug. Procarbazine hydrochloride is the alternative name used for this oncology small molecule developed by Pfizer for brain and central nervous system tumors.