Recent Updates
Recently added Catalysts

meningococcal B rLP2086 vaccine candidate

Phase 1

Meningitis, Meningococcal | Monoclonal antibody | Infectious Disease |Pfizer, Inc.|Last Updated: Aug 23, 2011

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedUNCONTROLLEDDMC
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

meningococcal B rLP2086 vaccine candidate · 1 trial · 1 indication

Phase 1 1
NCT00780806Safety And Blood Collection Study Of Meningococcal B Rlp2086 Vaccine In AdultsMeningitis, Meningococcal
COMPLETED60 Analytics
PHASE1COMPLETED
Safety And Blood Collection Study Of Meningococcal B Rlp2086 Vaccine In Adults
Meningitis, MeningococcalUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety of 3 doses of MnB rLP2086 vaccine candidate assessed by frequency of solicited local and systemic reactions collected for 7 days after each study vaccination; evaluation of occurrence of AE and SAE during the duration of study
Up to 2 years
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelSINGLE_GROUP

Treatment Arms

ArmTypeDescription
1EXPERIMENTALImmunization with one dose of MnB rLP2086 vaccine at 0, 1 and 6 months

Interventions

NameTypeDescription
meningococcal B rLP2086 vaccine candidateBIOLOGICALvaccine, 0.5 mL, 3 doses, 0 - 2 - 6 to 9 months
Blood drawPROCEDUREBlood draw
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 40 Years
SexALL
Healthy VolunteersYes
Study Sites3

Inclusion Criteria: * Healthy male or female subject between the ages of \>=18 and \<=40 years * Negative urine pregnancy test for all female subjects of childbearing potential prior to test article administration and at the completion of the study. * All female or male subjects who are biologicall...

Countries:Australia
Unlock Eligibility Criteria

Frequently asked questions about meningococcal B rLP2086 vaccine candidate

What is meningococcal B rLP2086 vaccine candidate used for?

Meningococcal B rLP2086 vaccine candidate is an investigational vaccine being studied for the prevention of meningitis and meningococcal disease. It is currently in Phase 1 clinical development and has not been approved by regulatory authorities.

Who makes meningococcal B rLP2086 vaccine candidate?

Meningococcal B rLP2086 vaccine candidate is being developed by Pfizer, Inc., a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE.

What phase is meningococcal B rLP2086 vaccine candidate in?

Meningococcal B rLP2086 vaccine candidate is in Phase 1 clinical development. It is an investigational vaccine and has not been approved for use. One Phase 1 trial has been completed.

What clinical trials is meningococcal B rLP2086 vaccine candidate in?

Meningococcal B rLP2086 vaccine candidate has one completed clinical trial, NCT00780806, titled 'Safety And Blood Collection Study Of Meningococcal B Rlp2086 Vaccine In Adults'. This Phase 1 study enrolled 60 participants in Australia and evaluated safety and blood collection.

How does meningococcal B rLP2086 vaccine candidate work?

Meningococcal B rLP2086 vaccine candidate is designed to elicit an immune response against Neisseria meningitidis serogroup B, the bacteria that causes meningococcal disease. It is intended to stimulate the production of antibodies that can neutralize the bacteria.