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SGN-15

Phase 2

Prostatic Neoplasms | Small molecule | Oncology |Pfizer, Inc.|Last Updated: Oct 24, 2011

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment160
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00031187Study of SGN-15, Antibody-Drug Conjugate, to Treat Hormone Refractory Prostate CancerPHASE2 COMPLETED 160Oct 1, 2000Jul 1, 2003Oct 24, 201111 United States
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
SGN-15 (cBR96-doxorubicin immunoconjugate)DRUG -
Taxotere (docetaxel)DRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexMALE
Healthy VolunteersNo
Study Sites11

BRIEF: Patients must have pathologically confirmed prostate cancer, which is refractory to hormone therapy. There must be evidence of advancing disease, determined by increasing bidimensional or unidimensional measurable tumor or an increasing PSA with documented metastatic disease. Patients must ...

Countries:United States
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