Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Premarin · 3 trials · 1 indication
| Arm | Type | Description |
|---|---|---|
| 1 | OTHER | - |
| 2 | ACTIVE_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| Premarin | DRUG | - |
| Premarin/MPA | DRUG | 0.625 mg/2.5 mg X4 |
| Provera 10 mg | DRUG | 2.5 mg of MPA, 4 tablets dissoved in water |
| Premarin/MPA 0.45 mg/1.5 mg | DRUG | - |
Inclusion Criteria: * For inclusion into the study, women must be healthy and postmenopausal (either naturally or surgically) between the ages of 35 and 70, inclusive. * Blood hormone levels must be consistent with a postmenopausal state (for specified subjects). * They can either be a non-smoker o...
Premarin is a small molecule drug being developed by Pfizer for use in postmenopause, primary ovarian insufficiency, and menopause. It is currently in Phase 1 clinical development, meaning it is investigational and not yet approved for these uses.
Premarin is developed by Pfizer, Inc., a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. The drug is currently in Phase 1 clinical trials for postmenopause, primary ovarian insufficiency, and menopause.
Premarin is in Phase 1 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities. All three completed clinical trials for Premarin were Phase 1 studies, and there are no active trials currently ongoing.
Premarin has completed three Phase 1 clinical trials. These include NCT00543634, comparing Premarin with MPA, PREMPRO, and Provera in healthy postmenopausal women; NCT00630435, comparing new formulations of Premarin with a reference formulation; and NCT00745173, evaluating a potential interaction between Premarin and bazedoxifene.
Premarin is not the same as PREMPRO, though they are related. PREMPRO is a combination product that contains Premarin (conjugated estrogens) and MPA (medroxyprogesterone acetate). Clinical trial NCT00543634 directly compared Premarin with MPA, PREMPRO, and Provera in healthy postmenopausal women.