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PF-05212372

Phase 1

Phase 1 | Small molecule | Other |Pfizer, Inc.|Last Updated: Aug 15, 2011

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment24

FDA Designations

No designations recorded

Clinical trial landscape

PF-05212372 · 1 trial · 5 indications

Phase 1 1
NCT01415102A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.Phase 1
COMPLETED24 Analytics
PHASE1COMPLETED
A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.
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Study Endpoints

Primary Endpoints

Number of Participants with Adverse Events as a Measure of Safety and Tolerability
14 days
Plasma pharmacokinetics
up to 72 hours post dose
Urine pharmacokinetics
up to 24 hours post dose
Urine Pharmacodynamics
up to 24 hours post dose
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
Cohort 1EXPERIMENTALSubjects will be assigned to receive either PF-05212372 or placebo in each period
Cohort 2EXPERIMENTALSubjects will be assigned to receive either PF-05212372 or placebo in each period

Interventions

NameTypeDescription
PF-05212372DRUGInhaled. Dose Level 1: 50 ug
PlaceboDRUGInhaled
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Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: Healthy subjects. (Healthy is defined as no clinically relevant abnormalities identified by a detailed medical history, full physical examination, including blood pressure and pulse rate measurement, 12-lead ECG and clinical laboratory tests). Exclusion Criteria: * Evidence or...

Countries:Belgium
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Frequently asked questions about PF-05212372

What is PF-05212372?

PF-05212372 is an investigational small molecule being developed by Pfizer, Inc. It is currently in Phase 1 clinical development. The drug is being studied for its safety, toleration, and pharmacokinetics in healthy volunteers.

What does PF-05212372 target?

PF-05212372 is a small molecule, but its specific molecular target has not been disclosed in the available information. The drug is being evaluated in early-stage clinical trials for safety and toleration.

Who makes PF-05212372?

PF-05212372 is being developed by Pfizer, Inc., which is publicly traded under the ticker symbol PFE on the New York Stock Exchange.

What phase is PF-05212372 in?

PF-05212372 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The drug is being studied in healthy volunteers to assess safety and pharmacokinetics.

What clinical trials is PF-05212372 in?

PF-05212372 has one completed Phase 1 clinical trial, identified as NCT01415102. This was a first-in-human study conducted in Belgium to evaluate the safety, toleration, and plasma concentration of single inhaled doses of the drug in healthy people.

Is PF-05212372 the same as any other drug?

PF-05212372 is the primary name for this investigational drug. No alternative names have been reported in the available information.