Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01165736 | To Calculate the Pharmacokinetics (Concentration of Compound in and Rate of Excretion From the Blood) Following a Very Low Dose of Compound Which Will Not Have Any Pharmacological Activity | PHASE1 | COMPLETED | 40 | — | — | Jul 1, 2010 | Aug 1, 2010 | Aug 24, 2010 | 1 | United Kingdom |
| Arm | Type | Description |
|---|---|---|
| Intravenous: PF-05186462 | ACTIVE_COMPARATOR | - |
| Oral: PF-05186462 | ACTIVE_COMPARATOR | - |
| Intravenous: PF-05089771 | ACTIVE_COMPARATOR | - |
| Oral: PF-05089771 | ACTIVE_COMPARATOR | - |
| Intravenous: PF-05150122 | ACTIVE_COMPARATOR | - |
| Oral: PF-05150122 | ACTIVE_COMPARATOR | - |
| Intravenous: PF-05241328 | ACTIVE_COMPARATOR | - |
| Oral: PF-05241328 | ACTIVE_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| PF-05186462 | DRUG | single intravenous infusion of 100 microgram |
| PF-05089771 | DRUG | single intravenous infusion of 100 microgram of PF-05089771 |
| PF-05150122 | DRUG | single intravenous administration of 100 microgram PF-05150122 |
| PF-05241328 | DRUG | single intravenous infusion of 100 microgram PF-05241328 |
Inclusion Criteria: * healthy male subjects between the ages of 18 and 50 years inclusive. (healthy is defined as no clinically relevant abnormalities identified by a detailed medical history, full physical examination including blood pressure and pulse rate measurement, 12-lead ECG and clinical la...