Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01370343 | Single Dose Study Of The Effect Of Cyclosporine On The Pharmacokinetics Of PF-04991532 In Health Volunteers | PHASE1 | COMPLETED | 12 | — | — | Jul 1, 2011 | Jul 1, 2011 | Sep 7, 2011 | 1 | Belgium |
| Arm | Type | Description |
|---|---|---|
| PF-04991532 alone | EXPERIMENTAL | - |
| PF-04991532 + cyclosporine | EXPERIMENTAL | - |
| Name | Type | Description |
|---|---|---|
| PF-04991532 alone | DRUG | a single dose of 150 mg PF-04991532, fasted |
| PF-04991532 + cyclosporine | DRUG | a single dose of 150 mg PF-04991532 + a single dose of 600 mg cyclosporine, fasted |
Inclusion Criteria: * Healthy male and/or female (non-childbearing potential) subjects between the ages of 18 and 55 years, inclusive. Healthy is defined as no clinically relevant abnormalities identified by a detailed medical history, full physical examination, including blood pressure and pulse r...