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PF-00592379

Phase 2

Impotence | Small molecule | Endocrine |Pfizer, Inc.|Last Updated: Aug 24, 2006

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment32

FDA Designations

No designations recorded

Clinical trial landscape

PF-00592379 · 1 trial · 1 indication

Phase 2 1
NCT00273416A Randomized Double Blind, Placebo Controlled Balanced 4-Way Crossover Study To Assess The Efficacy Of Single Oral DosesImpotence
COMPLETED32 Analytics
PHASE2COMPLETED
A Randomized Double Blind, Placebo Controlled Balanced 4-Way Crossover Study To Assess The Efficacy Of Single Oral Doses
ImpotenceUnlock trial analytics

Study Endpoints

Primary Endpoints

Duration of penile erections of greater than or equal to 60% rigidity as assessed by penile plethysmography (RigiScan PlusTM).

Secondary Endpoints

Duration and quality of penile erections recorded in a self-assessment diary.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeTREATMENT

Interventions

NameTypeDescription
PF-00592379DRUG -
Sildenafil 100mgDRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexMALE
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Erectile dysfunction, previous good response to an oral treatment for erectile dysfunction. Exclusion Criteria: * Patients with high blood pressure or certain heart conditions (e.g. angina, heart failure), regardless of whether treated or not. * Patients on nitrates or alpha...

Countries:NorwayUnited Kingdom
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Frequently asked questions about PF-00592379

What is PF-00592379 used for?

PF-00592379 is an investigational small molecule being developed for the treatment of impotence, also known as erectile dysfunction. It is in Phase 2 clinical development and is being studied in male patients aged 18 years and older.

Who makes PF-00592379?

PF-00592379 is being developed by Pfizer, Inc., a biopharmaceutical company traded on the New York Stock Exchange under the ticker symbol PFE. The drug is currently in Phase 2 clinical development for the treatment of impotence.

What phase is PF-00592379 in?

PF-00592379 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still undergoing clinical trials to assess its efficacy and safety for the treatment of impotence.

What clinical trials is PF-00592379 in?

PF-00592379 has been studied in one completed clinical trial, identified as NCT00273416. This was a randomized, double-blind, placebo-controlled, balanced 4-way crossover study that assessed the efficacy of single oral doses of the drug in 32 male participants with impotence.

Is PF-00592379 the same as any other drug?

No alternative names for PF-00592379 have been reported. The drug is identified solely by its development code PF-00592379 and is being investigated by Pfizer for the treatment of impotence.